Indolizine: a biologically active moiety

V Sharma, V Kumar - Medicinal Chemistry Research, 2014 - Springer
The discovery of camptothecin and its analogs was the major breakthrough through which
“Indolizine moiety” came into limelight. Although major part of the research on indolizine …

Terpenes and derivatives as a new perspective for pain treatment: a patent review

AG Guimarães, MR Serafini… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Terpenes are natural compounds found in several organisms belonging to the
animal and plant kingdoms. They constitute the largest class of natural products with> …

Echinocandins: production and applications

T Emri, L Majoros, V Tóth, I Pócsi - Applied microbiology and …, 2013 - Springer
The first echinocandin-type antimycotic (echinocandin B) was discovered in the 1970s. It
was followed by the isolation of more than 20 natural echinocandins. These cyclic lipo …

[PDF][PDF] Natural products as potential sources of antidiabetic drugs

PO Osadebe, EU Odoh, PF Uzor - 2014 - researchgate.net
Natural products have played and continue to play an invaluable role in the treatment of
various diseases and in drug discovery processes. It has remained a source of new …

Discovery, development, and regulation of natural products

J Krause, G Tobin - Using old solutions to new problems-natural …, 2013 - books.google.com
Natural products have historically been an extremely productive source for new medicines in
all cultures and continue to deliver a great variety of structural templates for drug discovery …

Anti-tubercular activity of substituted 7-methyl and 7-formylindolizines and in silico study for prospective molecular target identification

KN Venugopala, C Tratrat, M Pillay, FM Mahomoodally… - Antibiotics, 2019 - mdpi.com
Novel series of diversely substituted indolizines were designed, synthesized, and evaluated
for their in vitro anti-mycobacterial activity against H37Rv and multi-drug-resistant (MDR) …

Microwave-assisted improved regioselective synthesis of 3-benzoyl indolizine derivatives

G Sumanth, SM Saini, K Lakshmikanth… - Journal of Molecular …, 2023 - Elsevier
An efficient and facile method is developed to synthesize 3-benzoyl indolizines by two-
component reaction under microwave irradiation. A wide range of substrates could be …

Evaluation of anti–bacterial and anti–oxidant potential of andrographolide and echiodinin isolated from callus culture of Andrographis paniculata Nees

M Arifullah, ND Namsa, M Mandal… - Asian Pacific journal of …, 2013 - Elsevier
Objective To evaluate the anti–bacterial and anti–oxidant activity of andrographolide (AND)
and echiodinin (ECH) of Andrographis paniculata. Methods In this study, an attempt has …

Monoterpenes and their derivatives as agents for cardiovascular disease management: A systematic review and meta-analysis

EAP Silva, DM Santos, FO de Carvalho, IAC Menezes… - Phytomedicine, 2021 - Elsevier
Background Monoterpenes are one of the most studied plant's secondary metabolites, they
are found abundantly in essential oils of aromatic plants. They also have a great range of …

[PDF][PDF] Evaluation of antibacterial activities of compounds isolated from Sida rhombifolia Linn

S Woldeyes, L Adane, Y Tariku, D Muleta… - Malvaceae). Nat Prod …, 2012 - academia.edu
The main objective of this study was to isolate compounds from roots of Sida rhombifolia and
subsequently evaluate their antibacterial activities. Crude gradient extracts were obtained …