Dominant optic atrophy (DOA) is an inherited mitochondrial disease leading to specific
degeneration of retinal ganglion cells (RGCs), thus compromising transmission of visual …

Optical coherence tomography (OCT) is a noninvasive imaging technique used to
qualitatively and quantitatively analyze various layers of the retina. OCT of the retinal nerve …

Background Melanopsin-expressing retinal ganglion cells (mRGCs), intrinsically
photosensitive RGCs, mediate the light-based pupil response and the light entrainment of …

Advancements in ocular imaging have significantly broadened our comprehension of
mitochondrial retinopathies and optic neuropathies by examining the structural and …

Background and Objective: Retinal ischemia-reperfusion (IR) leads to massive loss of retinal
ganglion cells (RGC) and characterizes several blind-causing ophthalmic diseases …

Objective To investigate whether tert-Butylhydroquinone (TBHQ) can ameliorate oxidative
stress and inflammation induced by glutamate excitotoxicity, and mediate retinal ganglion …

Introduction: We aimed to study the change in the retinal perfusion in Leber's hereditary
optic neuropathy (LHON). Methods: Fourteen patients (28 eyes) diagnosed with LHON and …

Optical coherence tomography angiography (OCTA) is an emerging technique for non-
invasively imaging the ocular vasculature, enabling quantitative measurements of retinal …

(1) Background: The purpose of this study was to evaluate the thickness of retinal layers in
Leber hereditary optic neuropathy (LHON) in the atrophic stage compared with presumably …

Purpose: The photopic negative response (PhNR) is an electrophysiological method that
provides retinal ganglion cell function assessment using full-field stimulation that does not …