Many cuts to ruin: a comprehensive update of caspase substrates
U Fischer, RU Jänicke, K Schulze-Osthoff - Cell Death & Differentiation, 2003 - nature.com
Apoptotic cell death is executed by the caspase-mediated cleavage of various vital proteins.
Elucidating the consequences of this endoproteolytic cleavage is crucial for our …
Elucidating the consequences of this endoproteolytic cleavage is crucial for our …
Poly (ADP-ribose) polymerase-1 cleavage during apoptosis: an update
C Soldani, AI Scovassi - Apoptosis, 2002 - Springer
Poly (ADP-ribosylation) is a post-translational modification of proteins playing a crucial role
in many processes, including DNA repair and cell death. The best known poly (ADP …
in many processes, including DNA repair and cell death. The best known poly (ADP …
An alternative, nonapoptotic form of programmed cell death
S Sperandio, I de Belle… - Proceedings of the …, 2000 - National Acad Sciences
The term apoptosis often has been used interchangeably with the term programmed cell
death. Here we describe a form of programmed cell death that is distinct from apoptosis by …
death. Here we describe a form of programmed cell death that is distinct from apoptosis by …
[HTML][HTML] Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response
Necrosis has long been described as a consequence of physico-chemical stress and thus
accidental and uncontrolled. Recently, it is becoming clear that necrotic cell death is as well …
accidental and uncontrolled. Recently, it is becoming clear that necrotic cell death is as well …
Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus
I Baumann, W Kolowos, RE Voll, B Manger… - Arthritis & …, 2002 - Wiley Online Library
Objective To investigate the fate of apoptotic cells in the germinal centers (GCs) of patients
with systemic lupus erythematosus (SLE). Methods Lymph node biopsy specimens obtained …
with systemic lupus erythematosus (SLE). Methods Lymph node biopsy specimens obtained …
Cell death in the pathogenesis of systemic lupus erythematosus and lupus nephritis
P Mistry, MJ Kaplan - Clinical Immunology, 2017 - Elsevier
Nephritis is one of the most severe complications of systemic lupus erythematosus (SLE).
One key characteristic of lupus nephritis (LN) is the deposition of immune complexes …
One key characteristic of lupus nephritis (LN) is the deposition of immune complexes …
How apoptotic cells aid in the removal of their own cold dead bodies
Apoptotic cell clearance facilitates the removal of aged, damaged, infected or dangerous
cells although minimizing perturbation of surrounding tissues, and is a vital process in the …
cells although minimizing perturbation of surrounding tissues, and is a vital process in the …
Characterization of the necrotic cleavage of poly (ADP-ribose) polymerase (PARP-1): implication of lysosomal proteases
S Gobeil, CC Boucher, D Nadeau… - Cell Death & …, 2001 - nature.com
The poly (ADP-ribose) polymerase (PARP-1), a 113 kDa nuclear enzyme, is cleaved in
fragments of 89 and 24 kDa during apoptosis. This cleavage has become a useful hallmark …
fragments of 89 and 24 kDa during apoptosis. This cleavage has become a useful hallmark …
Low-temperature plasma treatment induces DNA damage leading to necrotic cell death in primary prostate epithelial cells
AM Hirst, MS Simms, VM Mann, NJ Maitland… - British journal of …, 2015 - nature.com
Background: In recent years, the rapidly advancing field of low-temperature atmospheric
pressure plasmas has shown considerable promise for future translational biomedical …
pressure plasmas has shown considerable promise for future translational biomedical …
SLE—a disease of clearance deficiency?
Systemic lupus erythematosus (SLE) is a multifactorial disease and its pathogenesis and
precise aetiology remain unknown. Under physiological conditions, neither apoptotic nor …
precise aetiology remain unknown. Under physiological conditions, neither apoptotic nor …