Targets of immune escape mechanisms in cancer: basis for development and evolution of cancer immune checkpoint inhibitors
Simple Summary The tumor immune escape mechanisms are key factors in cancer
progression and metastasis. They are an undeniable hurdle for successful cancer treatment …
progression and metastasis. They are an undeniable hurdle for successful cancer treatment …
[HTML][HTML] Immunometabolic dysfunction of natural killer cells mediated by the hypoxia-CD73 axis in solid tumors
AM Chambers, S Matosevic - Frontiers in molecular biosciences, 2019 - frontiersin.org
NK cell infiltration into solid tumors is often low and is largely represented by the poorly-
cytotoxic CD56bright subset. Numerous studies have demonstrated that CD73 …
cytotoxic CD56bright subset. Numerous studies have demonstrated that CD73 …
Adenosine 2B receptor expression on cancer cells promotes metastasis
Adenosine plays an important role in inflammation and tumor development, progression,
and responses to therapy. We show that an adenosine 2B receptor inhibitor (A2BRi) …
and responses to therapy. We show that an adenosine 2B receptor inhibitor (A2BRi) …
K4Nb6O17/Fe3N/α-Fe2O3/C3N4 as an enhanced visible light-driven quaternary photocatalyst for acetamiprid photodegradation, CO2 reduction, and cancer cells …
A new magnetic quaternary photocatalyst, K 4 Nb 6 O 17/α-Fe 2 O 3/Fe 3 N/gC 3 N 4, was
synthesized via a simple one-step thermal pyrolysis process. The prepared photocatalyst …
synthesized via a simple one-step thermal pyrolysis process. The prepared photocatalyst …
CD73–adenosine: a next-generation target in immuno-oncology
Cancer immunotherapy has entered in a new era with the development of first-generation
immune checkpoint inhibitors targeting the PD1/PD-L1 and CTLA-4 pathways. In this …
immune checkpoint inhibitors targeting the PD1/PD-L1 and CTLA-4 pathways. In this …
Glutathione in ovarian cancer: a double-edged sword
SC Nunes, J Serpa - International journal of molecular sciences, 2018 - mdpi.com
Glutathione (GSH) has several roles in a cell, such as a reactive oxygen species (ROS)
scavenger, an intervenient in xenobiotics metabolism and a reservoir of cysteine. All of these …
scavenger, an intervenient in xenobiotics metabolism and a reservoir of cysteine. All of these …
Adenosine and adenosine receptors in the immunopathogenesis and treatment of cancer
MH Kazemi, S Raoofi Mohseni… - Journal of Cellular …, 2018 - Wiley Online Library
Tumor cells overcome anti‐tumor responses in part through immunosuppressive
mechanisms. There are several immune modulatory mechanisms. Among them, adenosine …
mechanisms. There are several immune modulatory mechanisms. Among them, adenosine …
Purine-metabolising enzymes and apoptosis in cancer
M Camici, M Garcia-Gil, R Pesi, S Allegrini, MG Tozzi - Cancers, 2019 - mdpi.com
The enzymes of both de novo and salvage pathways for purine nucleotide synthesis are
regulated to meet the demand of nucleic acid precursors during proliferation. Among them …
regulated to meet the demand of nucleic acid precursors during proliferation. Among them …
Targeting A2 adenosine receptors in cancer
D Allard, M Turcotte, J Stagg - Immunology and cell biology, 2017 - Wiley Online Library
Tumor cells use various ways to evade anti‐tumor immune responses. Adenosine, a potent
immunosuppressive metabolite, is often found elevated in the extracellular tumor …
immunosuppressive metabolite, is often found elevated in the extracellular tumor …
Ag/AgCl@ Tubular g-C3N4 nanostructure as an enhanced visible light photocatalyst for the removal of organic dye compounds and biomedical waste under visible …
M Padervand, S Hajiahmadi - Journal of Photochemistry and Photobiology …, 2022 - Elsevier
Water contamination is a drastic worldwide issue menacing the whole biosphere and
disturbing people lives as long as human health is strongly depended on the drinkable form …
disturbing people lives as long as human health is strongly depended on the drinkable form …