Genome-wide association studies (GWAS) have provided insights into the genetic basis of
complex diseases. In the next step, integrative multi-omics approaches can characterize …

Osteoarthritis genetics has been transformed in the past decade through the application of
large-scale genome-wide association scans. So far, over 100 polymorphic DNA variants …

Research into the molecular genetics of osteoarthritis (OA) has been substantially bolstered
in the past few years by the implementation of powerful genome-wide scans that have …

Background Hip minimum joint space width (mJSW) provides a proxy for cartilage thickness.
This study aimed to conduct a genome-wide association study (GWAS) of mJSW to (i) …

Objective In this review, we have highlighted advances in genetics, genomics and
epigenetics in the field of osteoarthritis (OA) over the past year. Methods A literature search …

Rheumatoid arthritis (RA) seriously impairs the quality of life of sufferers. It has been shown
that Lycium barbarum polysaccharide (LBP), a natural active indigestible ingredient with …

Osteoarthritis is non-inflammatory degenerative joint arthritis, which exacerbates disability in
elder persons. The molecular mechanisms of osteoarthritis are elusive. Ubiquitination, one …

Objective Osteoarthritis (OA) is an age‐related disease characterized by articular cartilage
degeneration. It is largely heritable, and genetic screening has identified single‐nucleotide …

This study was conducted to examine the associations between genome-wide association
studies (GWAS)-important single nucleotide polymorphisms (SNPs) and knee osteoarthritis …

To address the complexity of osteoarthritis, integration of multitissue analyses by multiomics
approaches with the inclusion of longitudinal clinical data is necessary for a comprehensive …