Relaxed selection and the rapid evolution of reproductive genes

AL Dapper, MJ Wade - Trends in Genetics, 2020 - cell.com
Evolutionary genomic studies find that reproductive protein genes, those directly involved in
reproductive processes, diversify more rapidly than most other gene categories. Strong …

Sexual conflict and seminal fluid proteins: a dynamic landscape of sexual interactions

LK Sirot, A Wong, T Chapman… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Sexual reproduction requires coordinated contributions from both sexes to proceed
efficiently. However, the reproductive strategies that the sexes adopt often have the potential …

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

SU Jain, TJ Do, PJ Lund, AQ Rashoff, KL Diehl… - Nature …, 2019 - nature.com
Posterior fossa type A (PFA) ependymomas exhibit very low H3K27 methylation and express
high levels of EZHIP (Enhancer of Zeste Homologs Inhibitory Protein, also termed …

Divergence and conservation of the meiotic recombination machinery

M Arter, S Keeney - Nature Reviews Genetics, 2024 - nature.com
Sexually reproducing eukaryotes use recombination between homologous chromosomes to
promote chromosome segregation during meiosis. Meiotic recombination is almost …

Sex chromosomes and the evolution of sexual dimorphism: lessons from the genome

JE Mank - The American Naturalist, 2009 - journals.uchicago.edu
Females and males of many animals exhibit a striking array of sexual dimorphisms, ranging
from the primary differences of the gametes and gonads to the somatic differences often …

Synthesis and scope of the role of postmating prezygotic isolation in speciation

MD Garlovsky, E Whittington… - Cold Spring …, 2023 - cshperspectives.cshlp.org
How barriers to gene flow arise and are maintained are key questions in evolutionary
biology. Speciation research has mainly focused on barriers that occur either before mating …

Constraints and plasticity in genome and molecular-phenome evolution

EV Koonin, YI Wolf - Nature Reviews Genetics, 2010 - nature.com
Multiple constraints variously affect different parts of the genomes of diverse life forms. The
selective pressures that shape the evolution of viral, archaeal, bacterial and eukaryotic …

Molecular evolution across mouse spermatogenesis

EEK Kopania, EL Larson, C Callahan… - Molecular Biology …, 2022 - academic.oup.com
Genes involved in spermatogenesis tend to evolve rapidly, but we lack a clear
understanding of how protein sequences and patterns of gene expression evolve across this …

Izumo is part of a multiprotein family whose members form large complexes on mammalian sperm

DA Ellerman, J Pei, S Gupta, WJ Snell… - Molecular …, 2009 - Wiley Online Library
Izumo, a sperm membrane protein, is essential for gamete fusion in the mouse. It has an
Immunoglobulin (Ig) domain and an N‐terminal domain for which neither the functions nor …

Selection in the rapid evolution of gamete recognition proteins in marine invertebrates

VD Vacquier, WJ Swanson - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
Animal fertilization is governed by the interaction (binding) of proteins on the surfaces of
sperm and egg. In many examples presented herein, fertilization proteins evolve rapidly and …