Vascular endothelial growth factor (VEGF) and its receptors

G Neufeld, T Cohen, S Gengrinovitch… - The FASEB …, 1999 - Wiley Online Library
Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular
endothelial cells. Five VEGF isoforms are generated as a result of alternative splicing from a …

Endothelial cell migration during angiogenesis

L Lamalice, F Le Boeuf, J Huot - Circulation research, 2007 - Am Heart Assoc
Endothelial cell migration is essential to angiogenesis. This motile process is directionally
regulated by chemotactic, haptotactic, and mechanotactic stimuli and further involves …

The roles of growth factors in tendon and ligament healing

T Molloy, Y Wang, GAC Murrell - Sports medicine, 2003 - Springer
Tendon healing is a complex and highly-regulated process that is initiated, sustained and
eventually terminated by a large number and variety of molecules. Growth factors represent …

Mechanisms of normal and tumor-derived angiogenesis

M Papetti, IM Herman - American Journal of Physiology …, 2002 - journals.physiology.org
Often those diseases most evasive to therapeutic intervention usurp the human body's own
cellular machinery or deregulate normal physiological processes for propagation. Tumor …

Molecular and biological properties of vascular endothelial growth factor

N Ferrara - Journal of molecular medicine, 1999 - Springer
Vascular endothelial growth factor (VEGF) is a fundamental regulator of normal and
abnormal angiogenesis. Recent evidence indicates that VEGF is essential for embryonic …

[HTML][HTML] Role of vascular endothelial growth factor in the regulation of angiogenesis

N Ferrara - Kidney international, 1999 - Elsevier
Role of vascular endothelial growth factor in the regulation of angiogenesis. Compelling
evidence indicates that vascular endothelial growth factor (VEGF) is a fundamental regulator …

Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis

D Wei, X Le, L Zheng, L Wang, JA Frey, AC Gao… - Oncogene, 2003 - nature.com
Expression of vascular endothelial growth factor (VEGF), a key angiogenic protein, has been
linked with pancreatic cancer progression. However, the molecular basis for VEGF …

Fibroblast growth factors (FGFs) in cancer: FGF traps as a new therapeutic approach

M Presta, P Chiodelli, A Giacomini, M Rusnati… - Pharmacology & …, 2017 - Elsevier
Originally characterized as angiogenic factors, fibroblast growth factors (FGFs) are
pleiotropic factors that exert autocrine and paracrine functions on tumor and stromal cells …

The role of vascular endothelial growth factor in angiogenesis

N Ferrara, HP Gerber - Acta haematologica, 2001 - karger.com
Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen and an
angiogenic inducer as well as a mediator of vascular permeability. The biological effects of …

Transcriptional regulation of the vascular endothelial growth factor gene–a concert of activating factors

G Pagès, J Pouysségur - Cardiovascular research, 2005 - academic.oup.com
The vascular endothelial growth factor A (VEGF-A) is essential during embryonic
development as inactivation of only one allele of its gene results in embryonic lethality. Up …