Thoracic malignancies are often a difficult group of tumors to treat definitively as the
radiation doses needed to achieve a high probability for tumor control are often associated …

Background As costs of cancer care rise, the importance of documenting value in oncology
increases. Proton beam radiotherapy (PBT) has the potential to reduce toxicities in cancer …

Protontherapy is hadrontherapy's fastest-growing modality and a pillar in the battle against
cancer. Hadrontherapy's superiority lies in its inverted depth-dose profile, hence tumour …

Importance Proton beam radiotherapy (PBT) has the potential to reduce toxic effects in the
definitive management of locally advanced non–small cell lung cancer (NSCLC), but long …

Glioblastoma (GBM) is a devastating cancer of the brain with an extremely poor prognosis.
For this reason, besides clinical and preclinical studies, novel in vitro models for the …

Reirradiation (reRT) for locoregional recurrences poses unique challenges and risks; re-
treatment using proton beam radiotherapy (PBT) could prove advantageous. Assessing …

For patients with unresectable locally-advanced non-small cell lung cancer (LA-NSCLC),
concurrent chemoradiotherapy improves overall survival as compared to sequential …

Glioblastoma (GBM) is a devastating cancer of the brain with an extremely poor prognosis.
While X‐ray radiotherapy and chemotherapy remain the current standard, proton beam …

Stereotactic radiosurgery (SRS) involves the delivery of a highly conformal ablative dose of
radiation to both benign and malignant targets. This has traditionally been accomplished in …

Background and purpose In the model-based approach, patients qualify for proton therapy
when the reduction in risk of toxicity (ΔNTCP) obtained with IMPT relative to VMAT is larger …