The regulation of adipose tissue health by estrogens

BM Steiner, DC Berry - Frontiers in Endocrinology, 2022 - frontiersin.org
Obesity and its' associated metabolic diseases such as type 2 diabetes and cardiometabolic
disorders are significant health problems confronting many countries. A major driver for …

Endometriosis and cancer: exploring the role of macrophages

D Artemova, P Vishnyakova, E Khashchenko… - International Journal of …, 2021 - mdpi.com
Endometriosis and cancer have much in common, notably their burgeoning of cells in
hypoxic milieus, their invasiveness, and their capacity to trigger remodeling, vascularization …

Alzheimer's disease-associated protective variant Plcg2-P522R modulates peripheral macrophage function in a sex-dimorphic manner

HA Staley, JE Jernigan, MKL Bolen, AM Titus… - Journal of …, 2024 - Springer
Genome-wide association studies have identified a protective mutation in the phospholipase
C gamma 2 (PLCG2) gene which confers protection against Alzheimer's disease (AD) …

Ovariectomy provokes inflammatory and cardiovascular effects of endotoxemia in rats: Dissimilar benefits of hormonal supplements

MA El-Lakany, MA Fouda, HM El-Gowelli… - Toxicology and applied …, 2020 - Elsevier
The female gender is protected against immunological complications of endotoxemia. Here
we investigated whether gonadal hormone depletion by ovariectomy (OVX) uncovers …

Prospects for potential therapy targeting immune‑associated factors in endometriosis

W Zhang, K Li, A Jian, G Zhang… - Molecular Medicine …, 2025 - spandidos-publications.com
Endometriosis (EM) is a chronic inflammatory disease that is one of the most common
causes of gynecological systemic lesions in women before menopause. The most …

Sex hormones and immune regulation in ovarian cancer

R Zhao, W Lian, Q Xu - Discover Oncology, 2024 - Springer
Ovarian cancer continues to be a major cause of morbidity and mortality in women, with
immune regulation playing a critical role in its progression and treatment response. This …