Head and neck cancers (HNC) are the seventh most prevalent cancer type globally. Despite
their common categorisation, HNCs are a heterogeneous group of malignancies arising in …

Head and neck squamous cell carcinoma (HNSCC) outcomes remain stagnant, in part due
to a poor understanding of HNSCC biology. The importance of tumor heterogeneity as an …

Oral microbial dysbiosis contributes to the development of oral squamous cell carcinoma
(OSCC). Numerous studies have focused on variations in the oral bacterial microbiota of …

Aging is regarded as a dominant risk factor for cancer. Additionally, inflammation and
asthenic immune surveillance with aging may facilitate tumor formation and development …

Translational medicine aims to translate the most promising preclinical research into clinical
practice. Oncology is a continuously growing medical field: the scientific research on cancer …

This study focused on the expression of mitochondrial serine hydroxymethyltransferase
(SHMT2) in oral squamous cell carcinoma (OSCC) and its correlation with clinical traits and …

A challenge in cancer research is the definition of reproducible, reliable, and practical
models, which reflect the effects of complex treatment modalities and the heterogeneous …

Resistance to therapies targeting the epidermal growth factor receptor (EGFR), such as
cetuximab, remains a major roadblock in the search for effective therapeutic strategies in …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer in the
world, the 5-year survival rate of patients with HNSCC is still about 50% due to frequent …

Purpose: Poly lactic acid (PLA) combined with cisplatin-chloroquine nanoparticles
(CDDP/CQ-PLA NPs) and PLA combined with cisplatin nanoparticles (CDDP-PLA NPs) …