Lipoprotein (a): resurrected by genetics

F Kronenberg, G Utermann - Journal of internal medicine, 2013 - Wiley Online Library
Plasma lipoprotein (a)[L p (a)] is a quantitative genetic trait with a very broad and skewed
distribution, which is largely controlled by genetic variants at the LPA locus on chromosome …

Lipoprotein (a): impact by ethnicity and environmental and medical conditions

B Enkhmaa, E Anuurad, L Berglund - Journal of lipid research, 2016 - ASBMB
Levels of lipoprotein (a)[Lp (a)], a complex between an LDL-like lipid moiety containing one
copy of apoB, and apo (a), a plasminogen-derived carbohydrate-rich hydrophilic protein, are …

[HTML][HTML] National Lipid Association recommendations for patient-centered management of dyslipidemia: part 2

TA Jacobson, KC Maki, CE Orringer, PH Jones… - Journal of clinical …, 2015 - Elsevier
Abstract An Expert Panel convened by the National Lipid Association previously developed
a consensus set of recommendations for the patient-centered management of dyslipidemia …

[HTML][HTML] Lipoprotein (a): structure, pathophysiology and clinical implications

RC Maranhão, PO Carvalho, CC Strunz… - Arquivos brasileiros de …, 2014 - SciELO Brasil
The chemical structure of lipoprotein (a) is similar to that of LDL, from which it differs due to
the presence of apolipoprotein (a) bound to apo B100 via one disulfide bridge. Lipoprotein …

Relationship of apolipoprotein (a) isoform size with clearance and production of lipoprotein (a) in a diverse cohort

A Matveyenko, N Matienzo, H Ginsberg… - Journal of Lipid …, 2023 - ASBMB
Abstract Lipoprotein (a)[Lp (a)] has two main proteins, apoB100 and apo (a). High levels of
Lp (a) confer an increased risk for atherosclerotic cardiovascular disease. Most people have …

Familial hypercholesterolemia and elevated lipoprotein (a): cascade testing and other implications for contextual models of care

WJ Loh, DC Chan, P Mata, GF Watts - Frontiers in Genetics, 2022 - frontiersin.org
Elevated lipoprotein (a)[Lp (a)], a predominantly genetic disorder, is a causal risk factor for
atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valvular disease …

The impact of race and ethnicity on lipoprotein (a) levels and cardiovascular risk

G Reyes-Soffer - Current opinion in lipidology, 2021 - journals.lww.com
The impact of race and ethnicity on lipoprotein(a) levels an... : Current Opinion in Lipidology
The impact of race and ethnicity on lipoprotein(a) levels and cardiovascular risk : Current …

Associations of genetically predicted Lp (a)(lipoprotein [a]) levels with cardiovascular traits in individuals of European and African Ancestry

BA Satterfield, O Dikilitas, MS Safarova… - Circulation: Genomic …, 2021 - Am Heart Assoc
Background: Lp (a)(lipoprotein [a]) levels are higher in individuals of African ancestry (AA)
than in individuals of European ancestry (EA). We examined associations of genetically …

Correlation between chronic venous ulcer exudate proteins and clinical profile: A cross-sectional study

NRV Cavassan, CC Camargo, LG de Pontes… - Journal of …, 2019 - Elsevier
Chronic venous ulcers affect the quality of life of patients around the world. The aims of this
study were to identify the proteins expressed in chronic venous ulcer exudates, to categorize …

Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to …

MA Hall, A Verma, KD Brown-Gentry, R Goodloe… - PLoS …, 2014 - journals.plos.org
We performed a Phenome-wide association study (PheWAS) utilizing diverse genotypic and
phenotypic data existing across multiple populations in the National Health and Nutrition …