Ferroptosis, a form of cell death driven by iron-dependent lipid peroxidation, was identified
as a distinct phenomenon and named a decade ago. Ferroptosis has been implicated in a …

Ferroptosis is an iron-dependent lethal mechanism that can be activated in disease and is a
proposed target for cancer therapy. Ferroptosis is defined by the overwhelming …

Ferroptosis, a cell death modality characterized by iron-dependent lipid peroxidation, is
involved in the development of multiple pathological conditions, including ischemic tissue …

Aberrant RNA modifications lead to dysregulated gene expression and cancer progression.
Ribosomal RNA (rRNA) accounts for more than 80% of a cell's total RNA, but the functions …

Metastasis formation is a complex process, involving multiple crucial steps, which are
controlled by different regulatory mechanisms. In this context, the contribution of cancer …

Cardiovascular disease (CVD) is a major contributor to increasing morbidity and mortality
worldwide and seriously threatens human health and life. Cardiomyocyte death is …

Iron is an essential trace element for the human body, and its deficiency or excess can
induce a variety of biological processes. Plenty of evidences have shown that iron …

Understanding nephron loss is a primary strategy for preventing CKD progression. Death of
renal tubular cells may occur by apoptosis during developmental and regenerative …

Ferroptosis is a type of regulated cell death characterized by an excessive lipid peroxidation
of cellular membranes caused by the disruption of the antioxidant defense system and/or an …

Ferroptosis is an iron-dependent regulated cell death marked by excessive oxidative
phospholipids (PLs). The polyunsaturated fatty acids-containing phospholipids (PUFA-PLs) …