The systemic inflammatory response to cardiac surgery: implications for the anesthesiologist

DC Warltier, JG Laffey, JF Boylan… - The Journal of the …, 2002 - pubs.asahq.org
THE purpose of this review is to evaluate recent developments in our understanding of the
inflammatory response to cardiac surgery. Scientific knowledge in this field is continually …

Lung dysfunction following cardiopulmonary bypass

E Apostolakis, KS Filos, E Koletsis… - Journal of cardiac …, 2010 - Wiley Online Library
Background: It is well known by now that during open heart surgery many detrimental factors
are involved in lung injury. The influence mainly of cardiopulmonary bypass (CPB) …

Inflammatory response after coronary revascularization with or without cardiopulmonary bypass

R Ascione, CT Lloyd, MJ Underwood, AA Lotto… - The Annals of thoracic …, 2000 - Elsevier
Background. We sought to investigate the effect of multiple coronary artery bypass grafting
(CABG) with or without cardiopulmonary bypass (CPB) on the perioperative inflammatory …

Avoiding cardiopulmonary bypass in multivessel CABG reduces cytokine response and myocardial injury

S Wan, MB Izzat, TW Lee, IYP Wan, NLS Tang… - The Annals of thoracic …, 1999 - Elsevier
Background. Proinflammatory cytokines play a key role in the inflammatory cascade after
cardiopulmonary bypass and may induce cardiac dysfunction. We compared the production …

Predictors of atrial fibrillation after conventional and beating heart coronary surgery: a prospective, randomized study

R Ascione, M Caputo, G Calori, CT Lloyd… - Circulation, 2000 - Am Heart Assoc
Background—Atrial fibrillation (AF) increases the morbidity of CABG. The pathophysiology is
uncertain, and its prevention remains suboptimal. This prospective, randomized study was …

Side effects of cardiopulmonary bypass: what is the reality?

GJ Murphy, GD Angelini - Journal of cardiac surgery, 2004 - Wiley Online Library
Despite many years of clinical and experimental research, the contribution of
cardiopulmonary bypass (CPB) and cardioplegic arrest to morbidity and mortality following …

Systemic inflammation and cardiac surgery: an update

G Asimakopoulos - Perfusion, 2001 - journals.sagepub.com
Cardiac surgery with cardiopulmonary bypass (CPB) is associated with the development of
a systemic inflammatory response that can often lead to dysfunction of major organs. The …

[HTML][HTML] Reduced postoperative blood loss and transfusion requirement after beating-heart coronary operations: a prospective randomized study

R Ascione, S Williams, CT Lloyd… - The Journal of thoracic …, 2001 - Elsevier
Objective: Coronary artery bypass grafting on the beating heart through median sternotomy
is a relatively new treatment, which allows multiple revascularization without the use of …

Effect of cardiopulmonary bypass on pulmonary gas exchange: a prospective randomized study

CM Cox, R Ascione, AM Cohen, IM Davies… - The Annals of thoracic …, 2000 - Elsevier
Background. Conventional coronary artery bypass surgery is associated with postoperative
pulmonary dysfunction. Inflammation due to cardiopulmonary bypass has been regarded as …

Pulmonary outcomes of off-pump vs on-pump coronary artery bypass surgery in a randomized trial

GW Staton, WH Williams, EM Mahoney, J Hu, H Chu… - Chest, 2005 - Elsevier
Study objectives Comparison of pulmonary outcomes after off-pump coronary artery bypass
(OPCAB) vs on-pump coronary artery grafting with cardiopulmonary bypass (CABG/CPB) …