[HTML][HTML] Nutritional constituents of mulberry and their potential applications in food and pharmaceuticals: A review

B Jan, R Parveen, S Zahiruddin, MU Khan… - Saudi journal of …, 2021 - Elsevier
Mulberry is a fast growing deciduous plant found in wide variety of climatic, topographical
and soil conditions, and is widely distributed from temperate to subtropical regions. Due to …

Mulberry: A review of bioactive compounds and advanced processing technology

P Wen, TG Hu, RJ Linhardt, ST Liao, H Wu… - Trends in food science & …, 2019 - Elsevier
Background Historically, mulberry has been effectively used as a traditional medicine in Asia
for the treatment of various infectious and internal diseases. It is a rich source of bioactive …

Phytochemicals, pharmacological effects and molecular mechanisms of mulberry

J Hao, Y Gao, J Xue, Y Yang, J Yin, T Wu, M Zhang - Foods, 2022 - mdpi.com
There are numerous varieties of mulberry, and each has high medicinal value and is
regarded as a promising source of traditional medicines and functional foods. Nevertheless …

Mulberry (Morus alba L.) Leaf Extract and 1-Deoxynojirimycin Improve Skeletal Muscle Insulin Resistance via the Activation of IRS-1/PI3K/Akt Pathway in db/db Mice

CW Kang, M Park, HJ Lee - Life, 2022 - mdpi.com
Mulberry (Morus alba L.) leaves have been used to lower blood glucose in patients with
diabetes. We evaluated the effects of mulberry leaves extract (MLE) and 1-deoxynojirimycin …

The gut microbiota-produced indole-3-propionic acid confers the antihyperlipidemic effect of mulberry-derived 1-deoxynojirimycin

Y Li, W Xu, F Zhang, S Zhong, Y Sun, J Huo, J Zhu… - Msystems, 2020 - Am Soc Microbiol
Hyperlipidemia is a worldwide epidemic with an obvious gender disparity in incidence.
Modulations on gut microbiota by traditional Chinese medicines (TCM) are emerging as a …

1-Deoxynojirimycin: occurrence, extraction, chemistry, oral pharmacokinetics, biological activities and in silico target fishing

K Gao, C Zheng, T Wang, H Zhao, J Wang, Z Wang… - Molecules, 2016 - mdpi.com
1-Deoxynojirimycin (DNJ, C6H13NO4, 163.17 g/mol), an alkaloid azasugar or iminosugar, is
a biologically active natural compound that exists in mulberry leaves and Commelina …

Mulberry leaf powder ameliorate high starch-induced hepatic oxidative stress and inflammation in fish model

ZC Xv, GL He, X Wang, H Shun, YJ Chen… - Animal Feed Science and …, 2021 - Elsevier
This study aimed to explore the effects of mulberry leaf powder on glucose metabolism as
well as the underlying mechanisms. The largemouth bass (initial body weight: 10.12±0.06 g) …

Inhibition of Major Virulence Pathways of Streptococcus mutans by Quercitrin and Deoxynojirimycin: A Synergistic Approach of Infection Control

S Hasan, K Singh, M Danisuddin, PK Verma… - PLoS one, 2014 - journals.plos.org
Objectives To evaluate the synergistic effect of Quercitrin and Deoxynojirimycin (DNJ)
together with their individual inhibitory effect against virulence pathways of Streptococcus …

1-Deoxynojirimycin Alleviates Insulin Resistance via Activation of Insulin Signaling PI3K/AKT Pathway in Skeletal Muscle of db/db Mice

Q Liu, X Li, C Li, Y Zheng, G Peng - Molecules, 2015 - mdpi.com
1-Deoxynojirimycin (DNJ) is widely used for the treatment of diabetes mellitus as an inhibitor
of intestinal α-glucosidase. However, there are few reports about its effect on insulin …

Dietary supplementation of Morus nigra L. leaves decrease fat mass partially through elevating leptin-stimulated lipolysis in pig model

L Fan, Y Peng, D Wu, J Hu, G Yang, X Li - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Mulberry leaves are the dry leaves of Morus nigra L. trees,
which are widely cultivated in central and southern China. Mulberry has a long history of …