Compulsive behaviors have been associated with striatal hyperactivity. Parvalbumin-
positive striatal interneurons (PVIs) in the striatum play a crucial role in regulating striatal …

Animals often behave repetitively and predictably. These repetitive behaviors can have a
component that is learned and ingrained as habits, which can be evolutionarily …

Investigating the biophysiological substrates of psychiatric illnesses is of great interest to our
understanding of disorders' etiology, the identification of reliable biomarkers, and potential …

Autism spectrum disorder (ASD) is a highly prevalent, heterogenous neurodevelopmental
disorder. Neuroimaging methods such as functional, structural, and diffusion MRI have been …

The BTBR T+ Itpr3tf/J (BTBR) mouse displays elevated repetitive motor behaviors.
Treatment with the partial M1 muscarinic receptor agonist, CDD-0102A, attenuates …

In realistic sparse reward tasks, existing theoretical methods cannot be effectively applied
due to the low sampling probability ofrewarded episodes. Profound research on methods …

Prairie voles (Microtus ochrogaster) and Syrian, or golden, hamsters (Mesocricetus auratus)
are closely related to mice (Mus musculus) and are commonly used in studies of social …

Background Experience-dependent functional adaptation of nucleus accumbens (NAc)
circuitry underlies the development and expression of reward-motivated behaviors …

The involvement of parvalbumin (PV) interneurons in autism spectrum disorders (ASD)
pathophysiology has been widely described without clearly elucidating how their …

ABSTRACT A prominent electrophysiological feature of compulsive behaviours is striatal
hyperactivity, yet, its underlying regulatory processes still need to be characterised. Within …