Ocular neurodegenerative diseases: interconnection between retina and cortical areas
The possible interconnection between the eye and central nervous system (CNS) has been
a topic of discussion for several years just based on fact that the eye is properly considered …
a topic of discussion for several years just based on fact that the eye is properly considered …
[HTML][HTML] Cell fate decisions, transcription factors and signaling during early retinal development
R Diacou, P Nandigrami, A Fiser, W Liu… - Progress in retinal and …, 2022 - Elsevier
The development of the vertebrate eyes is a complex process starting from anterior-posterior
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …
Stem cells in the treatment of disease
HM Blau, GQ Daley - New England Journal of Medicine, 2019 - Mass Medical Soc
Stem-Cell Research and Clinical Application Stem cells have been the focus of hope, hype,
and a great deal of research. But what exactly is a stem cell, and what are its uses? This …
and a great deal of research. But what exactly is a stem cell, and what are its uses? This …
Iron oxide nanoparticles in regenerative medicine and tissue engineering
RP Friedrich, I Cicha, C Alexiou - Nanomaterials, 2021 - mdpi.com
In recent years, many promising nanotechnological approaches to biomedical research
have been developed in order to increase implementation of regenerative medicine and …
have been developed in order to increase implementation of regenerative medicine and …
[HTML][HTML] Retinitis pigmentosa: novel therapeutic targets and drug development
KY Wu, M Kulbay, D Toameh, AQ Xu, A Kalevar… - Pharmaceutics, 2023 - mdpi.com
Retinitis pigmentosa (RP) is a heterogeneous group of hereditary diseases characterized by
progressive degeneration of retinal photoreceptors leading to progressive visual decline. It …
progressive degeneration of retinal photoreceptors leading to progressive visual decline. It …
Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids
S Kim, A Lowe, R Dharmat, S Lee… - Proceedings of the …, 2019 - National Acad Sciences
Rod and cone photoreceptors are light-sensing cells in the human retina. Rods are
dominant in the peripheral retina, whereas cones are enriched in the macula, which is …
dominant in the peripheral retina, whereas cones are enriched in the macula, which is …
Retinitis pigmentosa: progress in molecular pathology and biotherapeutical strategies
W Liu, S Liu, P Li, K Yao - International Journal of Molecular Sciences, 2022 - mdpi.com
Retinitis pigmentosa (RP) is genetically heterogeneous retinopathy caused by
photoreceptor cell death and retinal pigment epithelial atrophy that eventually results in …
photoreceptor cell death and retinal pigment epithelial atrophy that eventually results in …
Pluripotent stem cell-derived retinal organoids for disease modeling and development of therapies
Retinal diseases constitute a genetically and phenotypically diverse group of clinical
conditions leading to vision impairment or blindness with limited treatment options …
conditions leading to vision impairment or blindness with limited treatment options …
Laminins in cellular differentiation
Basement membrane laminins (LNs) have been shown to modulate cellular phenotypes and
differentiation both in vitro and during organogenesis in vivo. At least 16 laminin isoforms …
differentiation both in vitro and during organogenesis in vivo. At least 16 laminin isoforms …
Retinal prostheses: Engineering and clinical perspectives for vision restoration
KY Wu, M Mina, JY Sahyoun, A Kalevar, SD Tran - Sensors, 2023 - mdpi.com
A retinal prosthesis, also known as a bionic eye, is a device that can be implanted to partially
restore vision in patients with retinal diseases that have resulted in the loss of …
restore vision in patients with retinal diseases that have resulted in the loss of …