The METTL3-m6A Epitranscriptome: Dynamic Regulator of Epithelial Development, Differentiation, and Cancer

A Maldonado López, BC Capell - Genes, 2021 - mdpi.com
Dynamic modifications on RNA, frequently termed both,“RNA epigenetics” and
“epitranscriptomics”, offer one of the most exciting emerging areas of gene regulation and …

KIAA1429/VIRMA promotes breast cancer progression by m6A‐dependent cytosolic HAS2 stabilization

N Li, Z Zhu, Y Deng, R Tang, H Hui, Y Kang… - EMBO …, 2023 - embopress.org
Abstract N6‐methyladenosine (m6A), the most abundant internal modification in eukaryotic
mRNA, plays important roles in many physiological and pathological processes, including …

METTL3-regulated m6A modification impairs the decidualization of endometrial stromal cells by regulating YTHDF2-mediated degradation of FOXO1 mRNA in …

X Li, J Jin, X Long, R Weng, W Xiong, J Liang… - Reproductive Biology …, 2023 - Springer
Background Endometriosis-related infertility is a common worldwide reproductive health
concern. Despite ongoing research, the causes of infertility remain unclear. Evidence …

N6-methyladenosine RNA modification in head and neck squamous cell carcinoma (HNSCC): current status and future insights

P Janakiraman, JP Jayaprakash, SV Muralidharan… - Medical Oncology, 2024 - Springer
Abstract N6-methyladenosine (m6A) plays a pivotal role in regulating epitranscriptomic
mechanisms and is closely linked to the normal functioning of diverse classes of RNAs, both …

Oral squamous cell carcinoma gene patterns connected with RNA methylation for prognostic prediction

X Wu, J Tang, B Cheng - Oral Diseases, 2024 - Wiley Online Library
Objectives To determine whether m6A/m1A/m5C/m7G/m6Am/Ψ‐related genes influence the
prognosis of a patient with oral squamous cell carcinoma. Materials and Methods We …

Extraction, characterization, and anticancer potential of extracellular polymeric substances from marine actinobacteria of Streptomyces species

ZM Noufal, P Sivaperumal… - Journal of advanced …, 2022 - journals.lww.com
To check the ability of the anticancer activity, the extracted extracellular polymeric
substances (EPS) from marine actinobacteria were done. Potential of the anticancer activity …

Prognostic and clinicopathological significance of MRC2 expression in head and neck squamous cell carcinoma

K vinayakam Gopalakrishnan, B Kannan… - Journal of Stomatology …, 2023 - Elsevier
Background Head and neck squamous cell carcinoma (HNSCC) is one of the most
aggressive types of cancers worldwide, with metastasis being the major cause of death …

Genetic alterations in CDKN2A interacting network and their putative association with head and neck squamous cell carcinoma

RS Sriram, P Anitha, K Balachander, P Chandra… - Human Gene, 2024 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) is a complex, polygenic disorder
involving the host, microbial, and environmental factors. The present study investigated the …

Construction of an m6A‐related lncRNA pair prognostic signature and prediction of the immune landscape in head and neck squamous cell carcinoma

C Zhou, S Wang, Z Shen, Y Shen, Q Li… - Journal of Clinical …, 2022 - Wiley Online Library
Background Mounting evidence indicates that aberrantly expressed N6‐methylandenosine
(m6A) modification regulators and long noncoding RNA (lncRNA) influence the …

Anti-Cancer Effects of Saraca asoca Flower Extract on Prostate Cancer Cell Line

A Choudhary, P Elumalai… - Journal of …, 2021 - archive.scholarstm.com
Background: Prostate cancer is the second most common cause of cancer deaths for men.
The role of plants in the prevention and treatment of disease has been known from the dawn …