Estrogen facilitates higher cognitive functions by exerting effects on brain regions such as
the prefrontal cortex and hippocampus. Estrogen induces spinogenesis and synaptogenesis …

Brain areas implicated in the stress response include the amygdala, hippocampus, and
prefrontal cortex. Traumatic stress can be associated with lasting changes in these brain …

In the third edition of her popular text, Sex Differences in Cognitive Abilities, Diane Halpern
tackles fundamental questions about the meaning of sex differences in cognition and why …

Until recently, tamoxifen, a nonsteroidal antiestrogen, was the mainstay of endocrine
treatment of breast cancer. However, new aromatase inhibitors that are many times more …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for
more than half of all dementia cases in the elderly. Interestingly, the clinical manifestations of …

It's obvious why only men develop prostate cancer and why only women get ovarian cancer.
But it is not obvious why women are more likely to recover language ability after a stroke …

ContextAlthough postmenopausal hormone replacement therapy (HRT) is widely used in
the United States, new evidence about its benefits and harms requires reconsideration of its …

Female and male brains differ. Differences begin early during development due to a
combination of genetic and hormonal events and continue throughout the lifespan of an …

Estrogen is an important hormone signal that regulates multiple tissues and functions in the
body. This review focuses on the neurotrophic and neuroprotective actions of estrogen in the …

Abstract Aromatase (estrogen synthetase; EC 1.14. 14.1) catalyzes the demethylation of
androgens' carbon 19, producing phenolic 18-carbon estrogens. Aromatase is most widely …