Diabetic kidney disease (DKD) is one of the fastest growing causes of chronic kidney
disease and associated morbidity and mortality. Preclinical research has demonstrated the …

Background Previous clinical trials and institutional studies have demonstrated that surgery
for the treatment of obesity (termed bariatric or metabolic surgery) reduces all-cause …

Importance Although metabolic surgery (defined as procedures that influence metabolism by
inducing weight loss and altering gastrointestinal physiology) significantly improves …

Background No data from randomised controlled trials of metabolic surgery for diabetes are
available beyond 5 years of follow-up. We aimed to assess 10-year follow-up after surgery …

Obesity is one of the major risk factors for the development of both impaired glucose
tolerance (IGT, or prediabetes) and type 2 diabetes (T2D), and its prevalence worldwide …

Microvascular and metabolic physiology are tightly linked. This Perspective reviews
evidence that 1) the relationship between hyperglycemia and microvascular dysfunction …

Obstructive sleep apnea (OSA) is a global disease with a rising incidence along with its
comorbidities, especially with metabolic syndrome. One of the main components …

Abstract Objective Modest weight loss (5%‐10%) is clinically meaningful in patients with
overweight or obesity. However, greater weight loss may be required to achieve …

The rapid rise of obesity during the past decades has coincided with a profound shift of our
living environment, including unhealthy dietary patterns, a sedentary lifestyle, and physical …

Background: Bariatric surgery improves glycemic control in patients with type 2 diabetes
mellitus (T2DM), but less is known about microvascular outcomes. Objective: To investigate …