Untargeted Metabolomics Identifies Biomarkers for MCADD Neonates in Dried Blood Spots

R Sebaa, M AlMogren, W Alseraty… - International Journal of …, 2023 - mdpi.com
Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is the most common inherited
mitochondrial metabolic disease of fatty acid β-oxidation, especially in newborns. MCADD is …

Associations of serum keratin 1 with thyroid function and immunity in Graves' disease

CW Cheng, WF Fang, JD Lin - Plos one, 2023 - journals.plos.org
Background Autoimmune thyroid disease (AITD) can cause enormous health burdens;
however, trustworthy biomarkers in identifying the onset and progression of AITD are limited …

Biomarker discovery in galactosemia: Metabolomics with UPLC/HRMS in dried blood spots

AN Alodaib, RM Nimer, R Alhumaidy… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction: Galactosemia (GAL) is a genetic disorder that results in disturbances in
galactose metabolism and can lead to life-threatening complications. However, the …

Metabolomics Panel Associated with Cystic Fibrosis-Related Diabetes toward Biomarker Discovery

M Mujammami, RM Nimer, M Al Mogren, R Almalki… - ACS …, 2024 - ACS Publications
The most prevalent comorbidity among cystic fibrosis (CF) patients is cystic fibrosis-related
diabetes (CFRD). CFRD has been linked to one of the worse clinical outcomes and a higher …

Demaghi, a polyherbal formulation, mitigates aluminum chloride-induced neurological impairment in mice: Insights from phytochemical analysis and behavioral …

H Ali, H Usman, W Ashraf, F Alqahtani, S Javaid… - Heliyon, 2023 - cell.com
Herbal products have been very popular in Pakistan for their curative significance against
various disorders. Demaghi (DEMG) is a widely used herbal product claimed to own natural …

A Distinctive Metabolomics Profile and Potential Biomarkers for Very Long Acylcarnitine Dehydrogenase Deficiency (VLCADD) Diagnosis in Newborns

R Sebaa, RH AlMalki, W Alseraty, AM Abdel Rahman - Metabolites, 2023 - mdpi.com
Very long-chain acylcarnitine dehydrogenase deficiency (VLCADD) is a rare inherited
metabolic disorder associated with fatty acid β-oxidation and characterized by genetic …

[HTML][HTML] Comparative untargeted metabolomics analysis of serum metabolic alterations in patients infected with hepatitis B virus genotypes B and C

M Deng, M Tong, F Fu, D Wei - Arabian Journal of Chemistry, 2023 - Elsevier
The clinicopathological characteristics and outcomes of patients infected with hepatitis B
virus (HBV) differ between genotypes B and C. However, the potential metabolic …

Serum metabolome analysis in hyperthyroid cats before and after radioactive iodine therapy

MA Bechtold, Y Lin, ML Miller, JM Prieto, CE Frederick… - Plos one, 2024 - journals.plos.org
Hyperthyroidism is the most common feline endocrinopathy. In hyperthyroid humans,
untargeted metabolomic analysis identified persistent metabolic derangements despite …

[HTML][HTML] Postprandial Metabolomic Profiling: Insights into Macronutrient-Specific Metabolic Responses in Healthy Individuals

A Alshahrani, SM Aleidi, M Al Dubayee, R AlMalki… - Nutrients, 2024 - mdpi.com
Background/Objectives: Understanding the metabolic responses to different macronutrients
is crucial for assessing their impacts on health. This study aims to investigate the …

[HTML][HTML] Metabolomic Effects of Liraglutide Therapy on the Plasma Metabolomic Profile of Patients with Obesity

AA Alfadda, AM Abdel Rahman, H Benabdelkamel… - Metabolites, 2024 - mdpi.com
Background: Liraglutide, a long-acting glucagon-like peptide-1 receptor agonist (GLP1RA),
is a well-established anti-diabetic drug, has also been approved for the treatment of obesity …