The production of monoclonal antibody (mAb) therapeutics, a rapidly growing multi-billion-
dollar enterprise in the biopharmaceutical industry, faces major challenges in achieving …

Chinese hamster ovary (CHO) cell lines have been widely used to produce recombinant
proteins. While the biosynthesis of recombinant proteins is energy-intensive, CHO cells …

Fed-batch culture is widely used in biopharmaceutical production owing to its superior
productivity; however, optimizing feeding trajectories remains a challenge. In this study, we …

In the last decade, biopharmaceutical production in mammalian systems has experienced
significant advances in product titres and quality, reaching multi-gram per litre bioprocesses …

This chapter discusses various challenges and opportunities with the adoption of these
technological advances in the commercial production and supply of biopharmaceuticals …

The term artificial intelligence (AI) has become pervasive in conversations about the future of
healthcare. AI has the potential to transform medicine through novel models of scientific …