Simple Summary Neuroblastoma is a pediatric tumor originating from the precursors of
sympathetic nerves. The disease is known for its high heterogeneity. Hence, developing …

Informative and realistic mouse models of high-risk neuroblastoma are central to
understanding mechanisms of tumour initiation, progression, and metastasis. They also play …

Cancer in children is rare with approximately 15,700 new cases diagnosed in the United
States annually. Through use of multimodality therapy (surgery, radiation therapy, and …

In the realm of animal breeding for sustainability, domestic camels have traditionally been
valued for their milk and meat production. However, key aspects such as zoometrics …

The RNA-binding protein LIN28B, identified as an independent risk factor in high-risk
neuroblastoma patients, is implicated in adverse treatment outcomes linked to metastasis …

Background Deletion of 1p is associated with poor prognosis in neuroblastoma, however
selected 1p-intact patients still experience poor outcomes. Since mutations of 1p genes may …

Neuroblastoma, the most common extracranial solid tumor in young children, arises from the
sympathetic nervous system. Our understanding of neuroblastoma has been improved by …

Neuroblastoma (NB), a complex pediatric cancer primarily affecting the adrenal medulla and
paraspinal sympathetic ganglia, presents significant clinical challenges due to its …

Neuroblastoma is the most common extra-cranial solid tumor of the sympathoadrenal cell
lineage, which is a unique pediatric malignancy with remarkable inter-and intra-tumoral …

Neuroblastoma (NB) is the most common extracranial solid tumour in childhood. NB is
thought to arise from the failed differentiation of neural crest progenitor cells that would …