Curcumin in liver diseases: a systematic review of the cellular mechanisms of oxidative stress and clinical perspective

MH Farzaei, M Zobeiri, F Parvizi, FF El-Senduny… - Nutrients, 2018 - mdpi.com
Oxidative stress has been considered a key causing factor of liver damage induced by a
variety of agents, including alcohol, drugs, viral infections, environmental pollutants and …

Curcumin as a functional food-derived factor: degradation products, metabolites, bioactivity, and future perspectives

T Tsuda - Food & function, 2018 - pubs.rsc.org
Curcumin is a polyphenol found in turmeric (Curcuma longa), used as a spice, in food
coloring, and as a traditional herbal medicine. It has been shown that curcumin has health …

The bioavailability, metabolism and microbial modulation of curcumin-loaded nanodelivery systems

R Chang, L Chen, M Qamar, Y Wen, L Li… - Advances in Colloid and …, 2023 - Elsevier
Curcumin (Cur), the major bioactive component of turmeric (Curcuma longa) possesses
many health benefits. However, low solubility, stability and bioavailability restricts its …

[HTML][HTML] Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice

S Prasad, AK Tyagi… - Cancer research and …, 2014 - synapse.koreamed.org
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma
longa) that has been associated with antioxidant, anti-inflammatory, anticancer, antiviral …

Curcumin nanoformulations: a review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment

O Naksuriya, S Okonogi, RM Schiffelers, WE Hennink - Biomaterials, 2014 - Elsevier
Curcumin, a natural yellow phenolic compound, is present in many kinds of herbs,
particularly in Curcuma longa Linn.(turmeric). It is a natural antioxidant and has shown many …

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - Elsevier
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

Exosomes for the enhanced tissue bioavailability and efficacy of curcumin

F Aqil, R Munagala, J Jeyabalan, AK Agrawal… - The AAPS journal, 2017 - Springer
Exosomes are extracellular microvesicles with a particle size of 30–100 nm and carry a
cargo of proteins, lipids, RNA, and DNA. Their properties of shuttling in-and-out of the cells …

Trends in advanced oral drug delivery system for curcumin: A systematic review

S Pan-On, P Dilokthornsakul… - Journal of Controlled …, 2022 - Elsevier
Although curcumin is globally recognized for its health benefits, its clinical application has
been restricted by its poor aqueous solubility and stability. To overcome these limitations …

Benefits of curcumin in brain disorders

A Bhat, AM Mahalakshmi, B Ray, S Tuladhar… - …, 2019 - Wiley Online Library
Curcumin is widely consumed in Asia either as turmeric directly or as one of the culinary
ingredients in food recipes. The benefits of curcumin in different organ systems have been …

Curcumin, a golden spice with a low bioavailability

A Siviero, E Gallo, V Maggini, L Gori, A Mugelli… - Journal of Herbal …, 2015 - Elsevier
In recent years several drugs have been developed deriving from traditional products and
current drug research is actively investigating the possible therapeutic roles of many …