Fibrosis is defined as an excessive deposition of connective tissue components and can
affect virtually every organ system, including the skin, lungs, liver and kidney. Fibrotic tissue …

The cellular complexity and functional diversity of the human immune system necessitate the
use of high-dimensional single-cell tools to uncover its role in multifaceted diseases such as …

Systemic sclerosis (SSc), also referred to as systemic scleroderma or scleroderma, is a rare,
complex immune-mediated connective tissue disease characterized by progressive skin …

Idiopathic pulmonary fibrosis (IPF) and systemic sclerosis-associated interstitial lung
disease (SSc-ILD) differ in the predominant demographics and identified genetic risk alleles …

Systemic sclerosis (SSc) has the highest cause-specific mortality of all the connective tissue
diseases, and the aetiology of this complex and heterogeneous condition remains an …

Systemic sclerosis is a complex autoimmune connective tissue disease which carries a
significant burden of disease-related morbidity including potentially life-threatening …

Systemic sclerosis (SSc) is a rare chronic autoimmune disease characterized by
vasculopathy, dysregulation of innate and adaptive immune responses, and progressive …

Abstract Systemic Sclerosis (SSc) pathogenesis involves multiple immunological, vascular
and fibroproliferative abnormalities that contribute to a severe and complex clinical picture …

Иммуновоспалительные ревматические заболевания (ИВРЗ)-большая группа
патологических состояний, в основе которых лежит нарушение иммунологической …

Increased endogenous DNA damage and type I interferon pathway activation have been
implicated in systemic sclerosis (SSc) pathogenesis. Because experimental evidence …