Lactadherin: an unappreciated haemostasis regulator and potential therapeutic agent
Abstract Lactadherin is a small (53–66 kDa) multifunctional glycoprotein belonging to the
secreted extracellular matrix protein family. It has a multi-domain structure and is involved in …
secreted extracellular matrix protein family. It has a multi-domain structure and is involved in …
Phagocytosis: Phenotypically simple yet a mechanistically complex process: Phagocytosis is a very complex but crucial process playing a pivotal role in embryonic …
V Kumar - International reviews of immunology, 2020 - Taylor & Francis
Phagocytosis is a pivotal immunological process, and its discovery by Elia Metchnikoff in
1882 was a step toward the establishment of the innate immune system as a separate …
1882 was a step toward the establishment of the innate immune system as a separate …
Up-regulation of TLR7-mediated IFN-α production by plasmacytoid dendritic cells in patients with systemic lupus erythematosus
K Sakata, S Nakayamada, Y Miyazaki, S Kubo… - Frontiers in …, 2018 - frontiersin.org
Objectives: Aberrant and persistent production of interferon-α (IFN-α) by plasmacytoid
dendritic cells (pDCs) is known to play a key role in the pathogenesis of systemic lupus …
dendritic cells (pDCs) is known to play a key role in the pathogenesis of systemic lupus …
Antibody-array-based proteomic screening of serum markers in systemic lupus erythematosus: a discovery study
A discovery study was carried out where serum samples from 22 systemic lupus
erythematosus (SLE) patients and matched healthy controls were hybridized to antibody …
erythematosus (SLE) patients and matched healthy controls were hybridized to antibody …
MFG-E8 (LACTADHERIN): a novel marker associated with cerebral amyloid angiopathy
P Marazuela, M Solé, A Bonaterra-Pastra… - Acta Neuropathologica …, 2021 - Springer
Brain accumulation of amyloid-beta (Aβ) is a crucial feature in Alzheimer´ s disease (AD)
and cerebral amyloid angiopathy (CAA), although the pathophysiological relationship …
and cerebral amyloid angiopathy (CAA), although the pathophysiological relationship …
Milk fat globule-EGF factor 8 suppresses the aberrant immune response of systemic lupus erythematosus-derived neutrophils and associated tissue damage
W Huang, J Wu, H Yang, Y Xiong, R Jiang… - Cell Death & …, 2017 - nature.com
Abnormal features of the systemic lupus erythematosus (SLE)-derived neutrophils, promoted
aberrant immune response, have inspired new studies of the induction of autoimmunity and …
aberrant immune response, have inspired new studies of the induction of autoimmunity and …
Clearance of apoptotic bodies, NETs, and biofilm DNA: implications for autoimmunity
M Radic - Frontiers in immunology, 2014 - frontiersin.org
Apoptosis and NETosis, two important pathways of programed cell death, differ in their
morphologic features and their effects on the immune system. In apoptosis, nuclear …
morphologic features and their effects on the immune system. In apoptosis, nuclear …
Incomplete clearance of apoptotic cells in systemic lupus erythematosus: pathogenic role and potential biomarker
JY Jung, CH Suh - International journal of rheumatic diseases, 2015 - Wiley Online Library
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with repeated
inflammation against multiple organs. Although its pathophysiology is not yet unveiled …
inflammation against multiple organs. Although its pathophysiology is not yet unveiled …
Comprehensive analysis of circRNAs, miRNAs, and mRNAs expression profiles and ceRNA networks in decidua of unexplained recurrent spontaneous abortion
X Liu, J Wu, H Nie, X Zhu, G Song, L Han… - Frontiers in Genetics, 2022 - frontiersin.org
The diagnosis and treatment of unexplained recurrent spontaneous abortion (URSA) are
subject to debate, because the exact underlying mechanisms remain unclear. To address …
subject to debate, because the exact underlying mechanisms remain unclear. To address …
[HTML][HTML] Alterations in expression of endometrial milk fat globule-EGF factor 8 (MFG-E8) and leukemia inhibitory factor (LIF) in patients with infertility and endometriosis
CR Schmitz, S Oehninger, VK Genro… - JBRA Assisted …, 2017 - ncbi.nlm.nih.gov
Objective The aim of this study was to compare the endometrial expression of milk fat
globule-EGF factor 8 (MFG-E8), its receptor integrin αvβ3, and leukemia inhibitory factor …
globule-EGF factor 8 (MFG-E8), its receptor integrin αvβ3, and leukemia inhibitory factor …