Artemisia annua is currently the only commercial source of the sesquiterpene lactone
artemisinin. Since artemisinin was discovered as the active component of A. annua in early …

Schistosomiasis is a helminthic disease affecting more than 200 million people in the tropics
as well as returning travellers. Treatment mainly relies on a single drug, praziquantel …

Background Schistosomiasis is an acute and chronic zoonotic parasitic disease caused by
trematode worms. The host inflammatory response to schistosome eggs leads to perioval …

Objective To evaluate the ameliorative role of grapefruit juice on the cytogenetic and
testicular damage induced by the antiarrythmic drug amiodarone in albino rats. Methods …

Praziquantel is the current drug of choice against schistosomiasis. The dependency on
praziquantel exclusively is problematic, given the spread of the disease and the threat of …

Schistosomiasis is a chronic parasitic disease caused by blood flukes (trematode) of the
genus Schistosoma. Schistosomiais is prevalent in tropical and sub-tropical areas …

Consideration of existing compounds always simplifies and shortens the long and difficult
process of discovering new drugs specifically for diseases of developing countries, an …

Background Artemisinin (ART) is an efficacious and safe anti-malarial drugs but has low oral
bioavailability and auto-induction profiles during multiple dosing. The pharmacokinetic …

Tetrabromobisphenol A (TBBPA) is currently the most widely-used brominated flame
retardant (BFR) and has been proven to have a very high toxicity to aquatic organisms …

The current treatment and control of schistosomiasis, rely on a single drug, praziquantel,
although, it has minor activity against juvenile stages of the parasite. Studies have shown …