Role of cholinergic signaling in Alzheimer's disease
ZR Chen, JB Huang, SL Yang, FF Hong - Molecules, 2022 - mdpi.com
Acetylcholine, a neurotransmitter secreted by cholinergic neurons, is involved in signal
transduction related to memory and learning ability. Alzheimer's disease (AD), a progressive …
transduction related to memory and learning ability. Alzheimer's disease (AD), a progressive …
The cholinergic system in the pathophysiology and treatment of Alzheimer's disease
Cholinergic synapses are ubiquitous in the human central nervous system. Their high
density in the thalamus, striatum, limbic system, and neocortex suggest that cholinergic …
density in the thalamus, striatum, limbic system, and neocortex suggest that cholinergic …
Neurobiochemical cross-talk between COVID-19 and Alzheimer's disease
MA Rahman, K Islam, S Rahman, M Alamin - Molecular neurobiology, 2021 - Springer
COVID-19, the global threat to humanity, shares etiological cofactors with multiple diseases
including Alzheimer's disease (AD). Understanding the common links between COVID-19 …
including Alzheimer's disease (AD). Understanding the common links between COVID-19 …
Resveratrol-selenium nanoparticles alleviate neuroinflammation and neurotoxicity in a rat model of Alzheimer's disease by regulating Sirt1/miRNA-134/GSK3β …
OAR Abozaid, MW Sallam, S El-Sonbaty… - … Trace Element Research, 2022 - Springer
Alzheimer's disease (AD) is a brain disorder associated with a gradual weakening in
neurocognitive functions, neuroinflammation, and impaired signaling pathways. Resveratrol …
neurocognitive functions, neuroinflammation, and impaired signaling pathways. Resveratrol …
Exercise-induced brain-derived neurotrophic factor expression: Therapeutic implications for Alzheimer's dementia
R Wang, RMD Holsinger - Ageing research reviews, 2018 - Elsevier
Emerging evidence indicates that moderate intensity aerobic exercise is positively
correlated with cognitive function and memory. However, the exact mechanisms underlying …
correlated with cognitive function and memory. However, the exact mechanisms underlying …
[HTML][HTML] Alzheimer's disease puzzle: delving into pathogenesis hypotheses
Alzheimer's disease (AD) is a prevalent neurodegenerative disease characterized by both
amnestic and non-amnestic clinical manifestations. It accounts for approximately 60-70% of …
amnestic and non-amnestic clinical manifestations. It accounts for approximately 60-70% of …
Chemical genetic activation of the cholinergic basal forebrain hippocampal circuit rescues memory loss in Alzheimer's disease
W Liu, J Li, M Yang, X Ke, Y Dai, H Lin, S Wang… - Alzheimer's research & …, 2022 - Springer
Background The degeneration of the cholinergic circuit from the basal forebrain to the
hippocampus contributes to memory loss in patients suffering from Alzheimer's disease …
hippocampus contributes to memory loss in patients suffering from Alzheimer's disease …
Cholinergic basal forebrain degeneration due to sleep-disordered breathing exacerbates pathology in a mouse model of Alzheimer's disease
L Qian, O Rawashdeh, L Kasas, MR Milne… - Nature …, 2022 - nature.com
Although epidemiological studies indicate that sleep-disordered breathing (SDB) such as
obstructive sleep apnea is a strong risk factor for the development of Alzheimer's disease …
obstructive sleep apnea is a strong risk factor for the development of Alzheimer's disease …
Reconsideration of anticholinesterase therapeutic strategies against Alzheimer's disease
H Wang, H Zhang - ACS chemical neuroscience, 2018 - ACS Publications
Alzheimer's disease (AD) is well-known as a severe neurodegeneration disease involving
complicated etiologies, and cholinesterase inhibition remain the prevailing mode of clinical …
complicated etiologies, and cholinesterase inhibition remain the prevailing mode of clinical …
Improving anti-neurodegenerative benefits of acetylcholinesterase inhibitors in Alzheimer's disease: are irreversible inhibitors the future?
DE Moss - International journal of molecular sciences, 2020 - mdpi.com
Decades of research have produced no effective method to prevent, delay the onset, or slow
the progression of Alzheimer's disease (AD). In contrast to these failures …
the progression of Alzheimer's disease (AD). In contrast to these failures …