microRNAs biogenesis, functions and role in tumor angiogenesis
T Annese, R Tamma, M De Giorgis, D Ribatti - Frontiers in oncology, 2020 - frontiersin.org
microRNAs (miRNAs) are small non-coding RNA molecules, evolutionary conserved. They
target more than one mRNAs, thus influencing multiple molecular pathways, but also …
target more than one mRNAs, thus influencing multiple molecular pathways, but also …
MicroRNA in control of gene expression: an overview of nuclear functions
C Catalanotto, C Cogoni, G Zardo - International journal of molecular …, 2016 - mdpi.com
The finding that small non-coding RNAs (ncRNAs) are able to control gene expression in a
sequence specific manner has had a massive impact on biology. Recent improvements in …
sequence specific manner has had a massive impact on biology. Recent improvements in …
Regulatory network of miRNA on its target: coordination between transcriptional and post-transcriptional regulation of gene expression
MicroRNAs (miRNAs) are a class of endogenous small noncoding RNAs that participate in a
majority of biological processes via regulating target gene expression. The post …
majority of biological processes via regulating target gene expression. The post …
RNA/DNA hybrid interactome identifies DXH9 as a molecular player in transcriptional termination and R-loop-associated DNA damage
R-loops comprise an RNA/DNA hybrid and displaced single-stranded DNA. They play
important biological roles and are implicated in pathology. Even so, proteins recognizing …
important biological roles and are implicated in pathology. Even so, proteins recognizing …
Nuclear functions of mammalian MicroRNAs in gene regulation, immunity and cancer
H Liu, C Lei, Q He, Z Pan, D Xiao, Y Tao - Molecular cancer, 2018 - Springer
MicroRNAs (miRNAs) are endogenous non-coding RNAs that contain approximately 22
nucleotides. They serve as key regulators in various biological processes and their …
nucleotides. They serve as key regulators in various biological processes and their …
Insulin receptor isoforms in physiology and disease: an updated view
A Belfiore, R Malaguarnera, V Vella… - Endocrine …, 2017 - academic.oup.com
The insulin receptor (IR) gene undergoes differential splicing that generates two IR isoforms,
IR-A and IR-B. The physiological roles of IR isoforms are incompletely understood and …
IR-A and IR-B. The physiological roles of IR isoforms are incompletely understood and …
MicroRNAs contribute to breast cancer invasiveness
I Fridrichova, I Zmetakova - Cells, 2019 - mdpi.com
Cancer statistics in 2018 highlight an 8.6 million incidence in female cancers, and 4.2 million
cancer deaths globally. Moreover, breast cancer is the most frequent malignancy in females …
cancer deaths globally. Moreover, breast cancer is the most frequent malignancy in females …
[HTML][HTML] The repertoire of serous ovarian cancer non-genetic heterogeneity revealed by single-cell sequencing of normal fallopian tube epithelial cells
The inter-differentiation between cell states promotes cancer cell survival under stress and
fosters non-genetic heterogeneity (NGH). NGH is, therefore, a surrogate of tumor resilience …
fosters non-genetic heterogeneity (NGH). NGH is, therefore, a surrogate of tumor resilience …
Epigenetics and microRNAs in cancer
A Ramassone, S Pagotto, A Veronese… - International journal of …, 2018 - mdpi.com
The ability to reprogram the transcriptional circuitry by remodeling the three-dimensional
structure of the genome is exploited by cancer cells to promote tumorigenesis. This …
structure of the genome is exploited by cancer cells to promote tumorigenesis. This …
ETMR: a tumor entity in its infancy
Abstract Embryonal tumor with Multilayered Rosettes (ETMR) is a relatively rare but typically
deadly type of brain tumor that occurs mostly in infants. Since the discovery of the …
deadly type of brain tumor that occurs mostly in infants. Since the discovery of the …