The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

Since 1995, more than 100 transgenic (Tg) mouse models of Alzheimer's disease (AD) have
been generated in which mutant amyloid precursor protein (APP) or APP/presenilin 1 (PS1) …

Background Two main genetic risks for sporadic Alzheimer's disease (AD) are a family
history and ɛ4 allele of apolipoprotein E. The brain and retina are part of the central nervous …

Alzheimer's disease (AD) is the most familiar type of dementia affecting elderly populations
worldwide. Studies of AD patients and AD transgenic mice have revealed alterations in the …

The murine models of Alzheimer's disease (AD) have advanced our understanding of the
pathophysiology. In vivo studies of the retina using optical coherence tomography (OCT) …

Animal models of disease are paramount to understand retinal development, the
pathophysiology of eye diseases, and to study neurodegeneration using optical coherence …

In Alzheimer's disease (AD), transgenic mouse models have established links between
abnormalities in the retina and those in the brain. APPNL-F/NL-F is a murine, humanized AD …

Alzheimer's disease (AD) may manifest retinal changes preceding brain pathology. A
transversal case-control study utilized spectral-domain OCT angiography (SD-OCTA) and …

Having a family history (FH+) of Alzheimer's disease (AD) and being a carrier of at least one
ɛ4 allele of the ApoE gene are two of the main risk factors for the development of AD. AD …

The purpose of the study is to demonstrate coherent optical tomography and
electroretinography techniques adopted from the human clinical practice to assess the …