Clinical development and potential of photothermal and photodynamic therapies for cancer

X Li, JF Lovell, J Yoon, X Chen - Nature reviews Clinical oncology, 2020 - nature.com
Light-activated, photosensitizer-based therapies have been established as safe modalities
of tumour ablation for numerous cancer indications. Two main approaches are available …

Photodynamic therapy for cancer: what's past is prologue

MR Hamblin - Photochemistry and photobiology, 2020 - Wiley Online Library
Abstract Thomas J Dougherty from Roswell Park Cancer Center played a major role in the
progress of photodynamic therapy (PDT) from a laboratory science into a real‐world clinical …

[HTML][HTML] Recent studies in photodynamic therapy for cancer treatment: From basic research to clinical trials

TE Kim, JE Chang - Pharmaceutics, 2023 - mdpi.com
Photodynamic therapy (PDT) is an emerging and less invasive treatment modality for
various types of cancer. This review provides an overview of recent trends in PDT research …

[HTML][HTML] Photochemical internalization for intracellular drug delivery. From basic mechanisms to clinical research

W Jerjes, TA Theodossiou, H Hirschberg… - Journal of clinical …, 2020 - mdpi.com
Photochemical internalisation (PCI) is a unique intervention which involves the release of
endocytosed macromolecules into the cytoplasmic matrix. PCI is based on the use of …

Photodynamic therapy in head and neck cancer: indications, outcomes, and future prospects

J Meulemans, P Delaere… - Current opinion in …, 2019 - journals.lww.com
The value of PDT in specific well-selected head and neck cancer clinical scenarios is well
established. The basic research field is rapidly evolving and experimental findings are …

A review of photodynamic therapy for neoplasms of the head and neck

FJ Civantos, B Karakullukcu, M Biel, CE Silver… - Advances in …, 2018 - Springer
Photodynamic therapy (PDT) involves the use of a phototoxic drug which is activated by low
powered laser light to destroy neoplastic cells. Multiple photosensitizers have been studied …

Novel vectors and administrations for mRNA delivery

C Bai, C Wang, Y Lu - Small, 2023 - Wiley Online Library
Abstract mRNA therapy has shown great potential in infectious disease vaccines, cancer
immunotherapy, protein replacement therapy, gene editing, and other fields due to its central …

Some Activities of PorphyChem Illustrated by the Applications of Porphyrinoids in PDT, PIT and PDI

B Habermeyer, R Guilard - Photochemical & Photobiological Sciences, 2018 - pubs.rsc.org
Photodynamic therapy is an innovative approach to treat diverse cancers and diseases that
involves the use of photosensitizing agents along with light of an appropriate wavelength to …

[HTML][HTML] Development of Biotechnological Photosensitizers for Photodynamic Therapy: Cancer Research and Treatment—From Benchtop to Clinical Practice

M Aires-Fernandes, R Botelho Costa… - Molecules, 2022 - mdpi.com
Photodynamic therapy (PDT) is a noninvasive therapeutic approach that has been applied
in studies for the treatment of various diseases. In this context, PDT has been suggested as …

[HTML][HTML] Photodynamic therapy in 3D cancer models and the utilisation of nanodelivery systems

L Mohammad-Hadi, AJ MacRobert, M Loizidou… - Nanoscale, 2018 - pubs.rsc.org
Photodynamic therapy (PDT) is the subject of considerable research in experimental cancer
models mainly for the treatment of solid cancerous tumours. Recent studies on the use of …