[HTML][HTML] Central and peripheral mechanisms involved in the control of GnRH neuronal function by metabolic factors

M Ruiz-Cruz, C Torres-Granados… - Current Opinion in …, 2023 - Elsevier
Gonadotropin-releasing hormone (GnRH) neurons are the final output pathway for the brain
control of reproduction. The activity of this neuronal population, mainly located at the …

[HTML][HTML] The galaninergic system: A target for cancer treatment

ML Sánchez, R Coveñas - Cancers, 2022 - mdpi.com
Simple Summary Peptidergic systems play an important role in cancer progression. The
galaninergic system (the peptide galanin and its receptors: galanin 1, 2 and 3) is involved in …

Spexin Diminishes Atrial Fibrillation Vulnerability by Acting on Galanin Receptor 2

D Li, Y Liu, C Li, Z Zhou, K Gao, H Bao, J Yang, G Xue… - Circulation, 2024 - ahajournals.org
BACKGROUND: G protein–coupled receptors play a critical role in atrial fibrillation (AF).
Spexin is a novel ligand of galanin receptors (GALRs). In this study, we investigated the …

[HTML][HTML] Identification of neurohypophysial hormones and the role of VT in the parturition of pregnant seahorses (Hippocampus erectus)

H Zhang, Y Liu, G Qin, Q Lin - Frontiers in Endocrinology, 2022 - frontiersin.org
Neurohypophysial hormones regulate the reproductive behavior of teleosts; however, their
role in the gestation and parturition of ovoviviparous fishes with male pregnancy …

Does exercise during a ketogenic diet effectively alter appetite sensation, appetite-regulating hormones, and body composition?

A Valinejad, K Khodaei - Experimental Biology and Medicine, 2022 - journals.sagepub.com
Exercise and diet are two essential interventions in weight control. The purpose of this study
was to compare the effectiveness of two exercise training types during a ketogenic diet (KD) …

[HTML][HTML] New evidence for SPX2 in regulating the brain-pituitary reproductive axis of half-smooth tongue sole (Cynoglossus semilaevis)

B Wang, K Wang, Z Tian, A Cui, X Liu, Z Jin… - Frontiers in …, 2022 - frontiersin.org
Spexin (SPX) is an evolutionarily conserved neuropeptide, which was first identified in
human proteome by data mining. Two orthologs (SPX1 and SPX2) are present in some non …

Exercise Training and Spexin Ameliorate Thyroid Changes in Obese Type 2-Diabetic Rats: The Possible Interlaying Mechanisms

FH Rizk, RAE Barhoma, MH El-Saka… - American Journal …, 2024 - journals.physiology.org
Thyroid dysfunction and diabetes mellitus are prevalent endocrine disorders that often
coexist and influence each other. The role of spexin (SPX) in diabetes and obesity is well …

[HTML][HTML] Circulating spexin is associated with body mass index and fat mass but not with physical activity and psychological parameters in women across a broad body …

M Suhs, A Stengel, A Rudolph, S Schaper… - Journal of Clinical …, 2022 - mdpi.com
Spexin (SPX) is a novel, widely expressed peptide, with anorexigenic effects demonstrated
in animal models and negatively correlated with body mass index (BMI) in humans. It …

Intracerebroventricular injection of spexin stimulates the hypothalamic-pituitary-testicular axis and increases the secretion of male reproductive hormones in rats

N Yilmaz, RZI Yasi̇n, A Yildiz - Annals of Anatomy-Anatomischer Anzeiger, 2024 - Elsevier
Background Male reproductive functions are regulated in the hypothalamic-pituitary-gonadal
(HPG) axis. Any problem in this axis would lead to the deterioration of reproductive …

[HTML][HTML] Cord Blood Spexin Level in Mothers with Obesity—Forecast of Future Obesity?

M Wojciechowska, PA Kolodziejski… - Children, 2023 - mdpi.com
Spexin (SPX) is a peptide that plays an important role in the regulation of food intake and
body weight (BW) by the effect on carbohydrate-lipid metabolism. However, the role of SPX …