Tannins are a heterogenous class of polyphenolic natural products with promising cancer
chemopreventive and therapeutic potential. Studies undertaken over the last 30 years have …

Endothelial dysfunction is an early pathophysiological feature and independent predictor of
poor prognosis in most forms of cardiovascular diseases. Epidemiological studies report an …

Interest in the use of traditional medicines for cancer prevention and treatment is increasing.
In vitro, in vivo, and clinical studies suggest the potential use of proteasome inhibitors as …

Biologically produced reactive oxygen species (ROS) are important signaling molecules in
the human body. Despite their importance under normal conditions, abnormal …

Developing nanocarrier systems with sufficient drug loading ability and efficient drug release
behavior in cells is a powerful strategy to maximize therapeutic efficacies and minimize side …

Although cisplatin has been used for decades to treat human cancer, some toxic side effects
and resistance are observed. It has been suggested that gold (III) complexes, containing …

Stat3 protein has an important role in oncogenesis and is a promising anticancer target.
Indirubin, the active component of a traditional Chinese herbal medicine, has been shown …

Curcumin (diferuloylmethane) is the major active ingredient of turmeric (Curcuma longa)
used in South Asian cuisine for centuries. Curcumin has been shown to inhibit the growth of …

Proteasome-mediated degradation is a common mechanism by which cells renew their
intracellular proteins and maintain protein homeostasis. In this process, the E3 ubiquitin …

Significant advancements have been noticed in cancer therapy for decades. Despite this,
there are still many critical challenges ahead, including multidrug resistance, drug instability …