Integrating new findings and examining clinical applications of pattern separation
Pattern separation, the ability to independently represent and store similar experiences, is a
crucial facet of episodic memory. Growing evidence suggests that the hippocampus …
crucial facet of episodic memory. Growing evidence suggests that the hippocampus …
Extra-hippocampal contributions to pattern separation
Pattern separation, or the process by which highly similar stimuli or experiences in memory
are represented by non-overlapping neural ensembles, has typically been ascribed to …
are represented by non-overlapping neural ensembles, has typically been ascribed to …
Rapid stimulation of human dentate gyrus function with acute mild exercise
Physical exercise has beneficial effects on neurocognitive function, including hippocampus-
dependent episodic memory. Exercise intensity level can be assessed according to whether …
dependent episodic memory. Exercise intensity level can be assessed according to whether …
Hippocampal maturity promotes memory distinctiveness in childhood and adolescence
A Keresztes, AR Bender… - Proceedings of the …, 2017 - National Acad Sciences
Adaptive learning systems need to meet two complementary and partially conflicting goals:
detecting regularities in the world versus remembering specific events. The hippocampus …
detecting regularities in the world versus remembering specific events. The hippocampus …
Missing links: The functional unification of language and memory (L∪ M)
The field of neurocognition is currently undergoing a significant change of perspective.
Traditional neurocognitive models evolved into an integrative and dynamic vision of …
Traditional neurocognitive models evolved into an integrative and dynamic vision of …
Acute moderate exercise improves mnemonic discrimination in young adults
Increasing evidence suggests that regular moderate exercise increases neurogenesis in the
dentate gyrus (DG) of the hippocampus and improves memory functions in both humans and …
dentate gyrus (DG) of the hippocampus and improves memory functions in both humans and …
The neurobiology of human fear generalization: meta-analysis and working neural model
Fear generalization to stimuli resembling a conditioned danger-cue (CS+) is a fundamental
dynamic of classical fear-conditioning. Despite the ubiquity of fear generalization in human …
dynamic of classical fear-conditioning. Despite the ubiquity of fear generalization in human …
Pattern separation beyond the hippocampus: A high‐resolution whole‐brain investigation of mnemonic discrimination in healthy adults
Episodic memory depends on the computational process of pattern separation in order to
establish distinct memory representations of similar episodes. Studies of pattern separation …
establish distinct memory representations of similar episodes. Studies of pattern separation …
Atypical neural topographies underpin dysfunctional pattern separation in temporal lobe epilepsy
Episodic memory is the ability to remember events from our past accurately. The process of
pattern separation is hypothesized to underpin this ability and is defined as the capacity to …
pattern separation is hypothesized to underpin this ability and is defined as the capacity to …
Pattern separation and source memory engage distinct hippocampal and neocortical regions during retrieval
RF Stevenson, ZM Reagh, AP Chun… - Journal of …, 2020 - Soc Neuroscience
Detailed representations of past events rely on the ability to form associations between items
and their contextual features (ie, source memory), as well as the ability to distinctly represent …
and their contextual features (ie, source memory), as well as the ability to distinctly represent …