N-Acetyl-Aspartyl-Glutamate in Brain Health and Disease
C Morland, K Nordengen - International Journal of Molecular Sciences, 2022 - mdpi.com
N-acetyl-aspartyl-glutamate (NAAG) is the most abundant dipeptide in the brain, where it
acts as a neuromodulator of glutamatergic synapses by activating presynaptic metabotropic …
acts as a neuromodulator of glutamatergic synapses by activating presynaptic metabotropic …
Green synthesis of CuO nanoparticles for biological applications
The up-to-date growth of nanoscience and nanotechnology has focused on various
applications of metal oxide nanoparticles (NPs) in different fields, such as life sciences …
applications of metal oxide nanoparticles (NPs) in different fields, such as life sciences …
Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites
Sulfur is an essential element of life. Thiol-containing metabolites in all organisms are
involved in the regulation of diverse biological processes. Especially, the microbiome …
involved in the regulation of diverse biological processes. Especially, the microbiome …
Ergothioneine in the brain
T Ishimoto, Y Kato - FEBS letters, 2022 - Wiley Online Library
Ergothioneine (ERGO) is a naturally occurring food‐derived antioxidant. Despite its
extremely hydrophilic properties, ERGO is easily absorbed from the gastrointestinal tract and …
extremely hydrophilic properties, ERGO is easily absorbed from the gastrointestinal tract and …
Gut microbiota in brain tumors: an emerging crucial player
B Lin, Z Ye, Z Ye, M Wang, Z Cao… - CNS Neuroscience & …, 2023 - Wiley Online Library
In recent decades, various roles of the gut microbiota in physiological and pathological
conditions have been uncovered. Among the many interacting pathways between the host …
conditions have been uncovered. Among the many interacting pathways between the host …
Antidepression of Xingpijieyu formula targets gut microbiota derived from depressive disorder
Y Li, L Yang, J Li, W Gao, Z Zhao… - CNS neuroscience & …, 2023 - Wiley Online Library
Objective This investigation aims to determine the antidepressant role of Xingpijieyu formula
(XPJYF) mediated via gut microbiota (GM)–brain axis. Methods We collected fecal …
(XPJYF) mediated via gut microbiota (GM)–brain axis. Methods We collected fecal …
Sleep Promotion by 3-Hydroxy-4-Iminobutyric Acid in Walnut Diaphragma juglandis Fructus
Insufficient sleep can produce a multitude of deleterious repercussions on various domains
of human well-being. Concomitantly, the walnut (Juglans mandshurica) confers numerous …
of human well-being. Concomitantly, the walnut (Juglans mandshurica) confers numerous …
Gut microbiota-associated metabolites and risk of ischemic stroke in REGARDS
Several metabolite markers are independently associated with incident ischemic stroke.
However, prior studies have not accounted for intercorrelated metabolite networks. We used …
However, prior studies have not accounted for intercorrelated metabolite networks. We used …
Sensitive quantification of short-chain fatty acids combined with global metabolomics in microbiome cultures
W Lin, FR García, EL Norin, D Kart… - Chemical …, 2023 - pubs.rsc.org
The microbiome has been identified to have a key role for the physiology of their human
host. One of the major impacts is the clearance of bacterial pathogens. We have now …
host. One of the major impacts is the clearance of bacterial pathogens. We have now …
Interventions for non-alcoholic liver disease: A gut microbial metabolites perspective
J Guo, CX Shi, QQ Zhang, W Deng… - Therapeutic …, 2022 - journals.sagepub.com
Over the past two decades, non-alcoholic fatty liver disease (NAFLD) has become a leading
burden of hepatocellular carcinoma and liver transplantation. Although the exact …
burden of hepatocellular carcinoma and liver transplantation. Although the exact …