The purpose of this study was to understand the combined effect of two polymers showing
drug–polymer interactions on amorphous stabilization and dissolution enhancement of …

The main objective of this study was to investigate different manufacturing processes
claimed to promote inclusion complexation between indomethacin and cyclodextrins in …

The main goal of this work was to test the ability of vibrational spectroscopy techniques to
differentiate between different polymorphic forms of fluconazole in pharmaceutical products …

The polymorphic control of active pharmaceutical ingredients (APIs) is a major challenge in
the manufacture of medicines. Crystallization methods that use supercritical carbon dioxide …

The occurrence of polymorphic transitions is a serious problem for pharmaceutical
companies, because it can affect the bioavailability of the final product. With several known …

Niclosamide, an anthelmintic drug recently repurposed for its activity against cancer,
crystallizes into three solvated forms, two monohydrates (NHa, NHb) and one anhydrous …

Indomethacin (INDO) is a synthetic non-steroidal antipyretic, analgesic, and anti-
inflammatory drug that commonly exists in both amorphous and crystalline states. Its …

In this work, the effect of crystallization parameters, ie, supersaturation, seeding, and
temperature, on the polymorphism and crystal size of a nonsteroidal anti-inflammatory drug …

Amorphous solid dispersions (SDs) are a promising approach to improve the dissolution
rate of and oral bioavailability of poorly water-soluble drugs. In some cases multi-phase …

Amorphous pharmaceuticals often possess a wide range of molecular conformations and
bonding arrangements. The x-ray pair distribution function (PDF) method is a powerful …