IL‐37 is a unique member of the IL‐1 family of cytokines, which functions as a natural
suppressor of inflammatory and immune responses. Immune and non‐immune cells …

Advances in sequencing technologies and increased access to sequencing services have
led to renewed interest in sequence and genome assembly. Concurrently, new applications …

INTRODUCTION Understanding the genetic differences that make us human is a long-
standing endeavor that requires the comprehensive discovery and comparison of all forms …

At least 150 indigenous African cattle breeds have been named, but the majority of African
cattle populations remain largely uncharacterized. As cattle breeds and populations in Africa …

Chromosome structural changes with nonrecurrent endpoints associated with genomic
disorders offer windows into the mechanism of origin of copy number variation (CNV). A …

DNA copy number variation has long been associated with specific chromosomal
rearrangements and genomic disorders, but its ubiquity in mammalian genomes was not …

IL‐37 is unique in the IL‐1 family in that unlike other members of the family, IL‐37 broadly
suppresses innate immunity. IL‐37 can be elevated in humans with inflammatory and …

The IL-1 family of cytokines encompasses eleven proteins that each share a similar-barrel
structure and bind to Ig-like receptors. Some of the IL-1-like cytokines have been well …

Compared with other mammals, the genomes of humans and other primates show an
enrichment of large, interspersed segmental duplications (SDs) with high levels of sequence …

To study the evolution of recombination rates in apes, we developed methodology to
construct a fine-scale genetic map from high-throughput sequence data from 10 Western …