Reactive Oxygen Species‐Scavenging Nanosystems in the Treatment of Diabetic Wounds

Y Xiong, X Chu, T Yu, S Knoedler… - Advanced …, 2023 - Wiley Online Library
Diabetic wounds are characterized by drug‐resistant bacterial infections, biofilm formation,
impaired angiogenesis and perfusion, and oxidative damage to the microenvironment …

Multifunctional hydrogels for the healing of diabetic wounds

T Xiang, Q Guo, L Jia, T Yin, W Huang… - Advanced …, 2024 - Wiley Online Library
The healing of diabetic wounds is hindered by various factors, including bacterial infection,
macrophage dysfunction, excess proinflammatory cytokines, high levels of reactive oxygen …

An immunomodulatory hydrogel by hyperthermia‐assisted self‐cascade glucose depletion and ROS scavenging for diabetic foot ulcer wound therapeutics

X Qi, E Cai, Y Xiang, C Zhang, XX Ge… - Advanced …, 2023 - Wiley Online Library
Current therapeutic protocols for diabetic foot ulcers (DFUs), a severe and rapidly growing
chronic complication in diabetic patients, remain nonspecific. Hyperglycemia‐caused …

[HTML][HTML] M2 macrophage-derived exosomes promote diabetic fracture healing by acting as an immunomodulator

Y Wang, Q Lin, H Zhang, S Wang, J Cui, Y Hu, J Liu… - Bioactive materials, 2023 - Elsevier
Diabetes mellitus is a chronically inflamed disease that predisposes to delayed fracture
healing. Macrophages play a key role in the process of fracture healing by undergoing …

Adipose Mesenchymal Stem Cell Derived Exosomes Promote Keratinocytes and Fibroblasts Embedded in Collagen/Platelet‐Rich Plasma Scaffold and Accelerate …

Y Wang, Y Zhang, T Li, K Shen, KJ Wang… - Advanced …, 2023 - Wiley Online Library
Engineered skin substitutes derived from human skin significantly reduce inflammatory
reactions mediated by foreign/artificial materials and are consequently easier to use for …

Recent perspective of polymeric biomaterial in tissue engineering–a review

MUA Khan, MA Aslam, MFB Abdullah, A Hasan… - Materials Today …, 2023 - Elsevier
Tissue engineering represents an advanced approach to treating patients who have
suffered tissue or organ loss or failure, with the ultimate goals of tissue restoration and …

3D-exosomes laden multifunctional hydrogel enhances diabetic wound healing via accelerated angiogenesis

H Peng, H Li, X Zhang, J Tang, Y Liang, L Qiao… - Chemical Engineering …, 2023 - Elsevier
Impaired vascular networks, local insufficiency of neovascularization, and tissue
inflammation caused by the accumulation of reactive oxygen species (ROS) and bacterial …

Three‐Step Regenerative Strategy: Multifunctional Bilayer Hydrogel for Combined Photothermal/Photodynamic Therapy to Promote Drug‐Resistant Bacteria‐Infected …

K Zha, W Zhang, W Hu, M Tan, S Zhang… - Advanced Functional …, 2024 - Wiley Online Library
The drug‐resistant bacterial‐infected skin wound is still a severe healthcare problem.
Uncontrolled bacterial infection, abundant reactive oxygen species (ROS) content, and …

Progress in pluronic F127 derivatives for application in wound healing and repair

S Li, C Yang, J Li, C Zhang, L Zhu, Y Song… - International Journal …, 2023 - Taylor & Francis
Pluronic F127 hydrogel biomaterial has garnered considerable attention in wound healing
and repair due to its remarkable properties including temperature sensitivity, injectability …

[HTML][HTML] Polysaccharide hydrogel platforms as suitable carriers of liposomes and extracellular vesicles for dermal applications

LP Jahromi, M Rothammer, G Fuhrmann - Advanced Drug Delivery …, 2023 - Elsevier
Lipid-based nanocarriers have been extensively investigated for their application in drug
delivery. Particularly, liposomes are now clinically established for treating various diseases …