DNA methylation is a conserved epigenetic modification that is important for gene regulation
and genome stability. Aberrant patterns of DNA methylation can lead to plant developmental …

Maintenance of genome stability requires control over the expression of transposable
elements (TEs), whose activity can have substantial deleterious effects on the host …

A large and significant portion of eukaryotic transcriptomes consists of noncoding RNAs
(ncRNAs) that have minimal or no protein-coding capacity but are functional. Diverse …

Plant genomes encode various small RNAs that function in distinct, yet overlapping, genetic
and epigenetic silencing pathways. However, the abundance and diversity of small-RNA …

The draft genome of the moss model, Physcomitrella patens, comprised approximately 2000
unordered scaffolds. In order to enable analyses of genome structure and evolution we …

Epigenetic modifications in DNA bases and histone proteins play important roles in the
regulation of gene expression and genome stability. Chemical modification of DNA base …

Since the human genome was sequenced, the term" epigenetics" is increasingly being
associated with the hope that we are more than just the sum of our genes. Might what we …

RNA-directed DNA methylation (RdDM) is the major small RNA-mediated epigenetic
pathway in plants. RdDM requires a specialized transcriptional machinery that comprises …

Nucleosome remodelers of the DDM1/Lsh family are required for DNA methylation of
transposable elements, but the reason for this is unknown. How DDM1 interacts with other …

INTRODUCTION Epigenetic modifications to chromatin, such as the methylation of DNA
cytosines, carry regulatory information across the generations in plants and animals …