Background Plasmodium vivax infects an estimated 7 million people every year. Previously,
vivax malaria was perceived as a benign condition, particularly when compared to …

After a successful invasion, malaria parasite Plasmodium falciparum extensively remodels
the infected erythrocyte cellular architecture, conferring cytoadhesive properties to the …

Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Plasmodium vivax is the second most prevalent cause of malaria worldwide and the leading
cause of malaria outside of Africa. Although infections are seldom fatal clinical disease can …

Parasites of the genus Plasmodium have a complex life cycle. They alternate between their
final mosquito host and their intermediate hosts. The parasite can be either extra-or …

More than one-third of the world's population is exposed to Plasmodium vivax malaria,
mainly in Asia. P. vivax preferentially invades reticulocytes (immature red blood cells) …

Glycophorins are heavily glycosylated sialoglycoproteins of human and animal erythrocytes.
In humans, there are four glycophorins: A, B, C and D. Glycophorins play an important role in …

The ability to culture pathogenic organisms substantially enhances the quest for
fundamental knowledge and the development of vaccines and drugs. Thus, the elaboration …

The ability of the intraerythrocytic Plasmodium spp. to form spontaneous rosettes with
uninfected red blood cells (URBCs) has been observed in the medically important malaria …

Malaria remains a major cause of mortality in African children, with no adjunctive treatments
currently available to ameliorate the severe clinical forms of the disease. Rosetting, the …