Bacterial defences: mechanisms, evolution and antimicrobial resistance

WPJ Smith, BR Wucher, CD Nadell… - Nature Reviews …, 2023 - nature.com
Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …

Ecology and genomics of Actinobacteria: new concepts for natural product discovery

DA van Bergeijk, BR Terlouw, MH Medema… - Nature Reviews …, 2020 - nature.com
Actinobacteria constitute a highly diverse bacterial phylum with an unrivalled metabolic
versatility. They produce most of the clinically used antibiotics and a plethora of other natural …

Disease suppressive soils: new insights from the soil microbiome

D Schlatter, L Kinkel, L Thomashow, D Weller… - …, 2017 - Am Phytopath Society
Soils suppressive to soilborne pathogens have been identified worldwide for almost 60
years and attributed mainly to suppressive or antagonistic microorganisms. Rather than …

Molecular regulation of antibiotic biosynthesis in Streptomyces

G Liu, KF Chater, G Chandra, G Niu… - … and molecular biology …, 2013 - Am Soc Microbiol
Streptomycetes are the most abundant source of antibiotics. Typically, each species
produces several antibiotics, with the profile being species specific. Streptomyces coelicolor …

The TetR family of regulators

L Cuthbertson, JR Nodwell - Microbiology and Molecular Biology …, 2013 - Am Soc Microbiol
The most common prokaryotic signal transduction mechanisms are the one-component
systems in which a single polypeptide contains both a sensory domain and a DNA-binding …

Quorum quenching enzymes

S Fetzner - Journal of biotechnology, 2015 - Elsevier
Bacteria use cell-to-cell communication systems based on chemical signal molecules to
coordinate their behavior within the population. These quorum sensing systems are …

Regulation of antibiotic production in Actinobacteria: new perspectives from the post-genomic era

HU Van Der Heul, BL Bilyk, KJ McDowall… - Natural product …, 2018 - pubs.rsc.org
Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …

Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis

RF Little, C Hertweck - Natural Product Reports, 2022 - pubs.rsc.org
Review covering up to mid-2021 The structure of polyketide and non-ribosomal peptide
natural products is strongly influenced by how they are released from their biosynthetic …

The role of antibiotics and antibiotic resistance in nature

RI Aminov - Environmental microbiology, 2009 - Wiley Online Library
Investigations of antibiotic resistance from an environmental prospective shed new light on a
problem that was traditionally confined to a subset of clinically relevant antibiotic‐resistant …

Genomic basis for natural product biosynthetic diversity in the actinomycetes

M Nett, H Ikeda, BS Moore - Natural product reports, 2009 - pubs.rsc.org
Covering: up to mid-2009 The phylum Actinobacteria hosts diverse high G+ C, Gram-
positive bacteria that have evolved a complex chemical language of natural product …