Biological molecules are often highly dynamic, and this flexibility can be critical for function.
The large range of sampled timescales and the fact that many of the conformers that are …

Transition metals have been recognized and studied primarily in the context of their
essential roles as structural and metabolic cofactors for biomolecules that compose living …

To date, 146 different mutations in superoxide dismutase 1 (SOD1) have been identified in
patients with familial amyotrophic lateral sclerosis (ALS). The mean age of disease onset in …

Molecules of the plant world are proving their effectiveness in countering, slowing down, and
regressing many diseases. The resveratrol for its intrinsic properties related to its stilbene …

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease presenting as sporadic
(sALS) or familial (fALS) forms. Even if the list of the genes underlining ALS greatly …

The most common cause of amyotrophic lateral sclerosis (ALS) is mutations in superoxide
dismutase-1 (SOD1). Since there is evidence for the involvement of non-neuronal cells in …

Mitochondria have been proposed as targets for toxicity in amyotrophic lateral sclerosis
(ALS), a progressive, fatal adult-onset neurodegenerative disorder characterized by the …

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder that
causes selective death of motor neurons followed by paralysis and death. A subset of ALS …

A common cause of amyotrophic lateral sclerosis (ALS) is mutations in the gene encoding
superoxide dismutase-1. There is evolving circumstantial evidence that the wild-type protein …

By unknown mechanisms, the symptoms of amyotrophic lateral sclerosis (ALS) seem to
spread along neuroanatomical pathways to engulf the motor nervous system. The rate at …