Cu-catalyzed click reaction in carbohydrate chemistry

VK Tiwari, BB Mishra, KB Mishra, N Mishra… - Chemical …, 2016 - ACS Publications
Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …

Antituberculosis drugs: ten years of research

YL Janin - Bioorganic & medicinal chemistry, 2007 - Elsevier
Tuberculosis is today amongst the worldwide health threats. As resistant strains of
Mycobacterium tuberculosis have slowly emerged, treatment failure is too often a fact …

Fruitful decade for antileishmanial compounds from 2002 to late 2011

H Hussain, A Al-Harrasi, A Al-Rawahi, IR Green… - Chemical …, 2014 - ACS Publications
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …

Fighting tuberculosis: an old disease with new challenges

RP Tripathi, N Tewari, N Dwivedi… - Medicinal Research …, 2005 - Wiley Online Library
Tuberculosis (TB) caused by Mycobacterium tuberculosis remains a leading cause of
mortality worldwide into 21st century. The mortality and spread of this disease has further …

An overview of metal-free synthetic routes to isoxazoles: the privileged scaffold

S Das, K Chanda - RSC advances, 2021 - pubs.rsc.org
In the field of drug discovery, isoxazole is a five-membered heterocyclic moiety commonly
found in many commercially available drugs. In view of their enormous significance, it is …

Synthesis and antitubercular screening of imidazole derivatives

J Pandey, VK Tiwari, SS Verma, V Chaturvedi… - European journal of …, 2009 - Elsevier
A series of imidazole based compounds were synthesized by reacting simple imidazoles
with alkyl halides or alkyl halocarboxylate in presence of tetrabutylammonium bromide …

New small-molecule synthetic antimycobacterials

L Ballell, RA Field, K Duncan… - Antimicrobial agents and …, 2005 - Am Soc Microbiol
Drugs for treating tuberculosis (TB) have been available for over half a century, and yet the
incidence of disease worldwide continues to rise year by year. In 2002, the last year for …

Recent advances in new structural classes of anti-tuberculosis agents

A Nayyar, R Jain - Current medicinal chemistry, 2005 - ingentaconnect.com
Tuberculosis (TB) is one of the most devastating diseases primarily due to several decades
of neglect, and presents a global health threat of escalating proportions. TB is the second …

Tetrabutylammonium hydrogen sulfate catalyzed eco-friendly and efficient synthesis of glycosyl 1, 4-dihydropyridines

N Tewari, N Dwivedi, RP Tripathi - Tetrahedron Letters, 2004 - Elsevier
An efficient and eco-friendly synthesis of glycosyl 1, 4-dihydropyridines has been achieved
by a three-component reaction of β-keto esters or ketones, enamines and glycosyl …

Development of Diverse Range of Biologically Relevant Carbohydrate‐Containing Molecules: Twenty Years of Our Journey

VK Tiwari - The Chemical Record, 2021 - Wiley Online Library
There is an increasing demand for significant amount of carbohydrate‐containing molecules
owing to their complete chemical, biological, and pharmacological investigations to better …