The constructive and destructive impact of autophagy on both genders' reproducibility, a comprehensive review

M Samare-Najaf, A Neisy, A Samareh, D Moghadam… - Autophagy, 2023 - Taylor & Francis
Reproduction is characterized by a series of massive renovations at molecular, cellular, and
tissue levels. Recent studies have strongly tended to reveal the involvement of basic …

[HTML][HTML] Autophagy in endometriosis

HL Yang, J Mei, KK Chang, WJ Zhou… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Endometriosis (EMS) is a common gynecologic disease that causes chronic pelvic pain,
dysmenorrhea, and infertility in women. The doctrine of menstruation back flow planting and …

Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence

H Lu, HL Yang, WJ Zhou, ZZ Lai, XM Qiu, Q Fu… - Autophagy, 2021 - Taylor & Francis
Deficiency in decidualization has been widely regarded as an important cause of
spontaneous abortion. Generalized decidualization also includes massive infiltration and …

Increased activity of osteocyte autophagy in ovariectomized rats and its correlation with oxidative stress status and bone loss

Y Yang, X Zheng, BO Li, S Jiang, L Jiang - Biochemical and biophysical …, 2014 - Elsevier
Objectives The objectives of the present study were to investigate ovariectomy on autophagy
level in the bone and to examine whether autophagy level is associated with bone loss and …

Sex differences in autophagy contribute to female vulnerability in Alzheimer's disease

EE Congdon - Frontiers in neuroscience, 2018 - frontiersin.org
Alzheimer's disease (AD) is the most common form of dementia, with over 5. 4 million cases
in the US alone (Alzheimer's Association,). Clinically, AD is defined by the presence of …

[HTML][HTML] Targeting a mTOR/autophagy axis: A double-edged sword of rapamycin in spontaneous miscarriage

MY Li, HH Shen, XY Cao, XX Gao, FY Xu, SY Ha… - Biomedicine & …, 2024 - Elsevier
Immune dysfunction is a primary culprit behind spontaneous miscarriage (SM). To address
this, immunosuppressive agents have emerged as a novel class of tocolytic drugs …

HIF-1α/BNIP3-mediated autophagy contributes to the luteinization of granulosa cells during the formation of corpus luteum

Z Tang, Z Zhang, Q Lin, R Xu, J Chen… - Frontiers in cell and …, 2021 - frontiersin.org
During the luteinization after ovulation in mammalian ovary, the containing cells undergo an
energy consuming function re-determination process to differentiate into luteal cells under …

The Autophagy Gene Atg16L1 is Necessary for Endometrial Decidualization

AK Oestreich, SB Chadchan, P Popli… - …, 2020 - academic.oup.com
Uterine receptivity is critical for establishing and maintaining pregnancy. For the
endometrium to become receptive, stromal cells must differentiate into decidual cells …

Hypoxia and reproductive health: The role of hypoxia in the development and progression of endometriosis

WN Li, MH Wu, SJ Tsai - Reproduction, 2021 - rep.bioscientifica.com
Endometriosis is a benign gynecological disease that affects about 10% women of
reproductive age. Patients with endometriosis suffer from long-term coexistence with …

PI3K/AKT/mTOR pathway promotes progestin resistance in endometrial cancer cells by inhibition of autophagy

H Liu, L Zhang, X Zhang, Z Cui - OncoTargets and therapy, 2017 - Taylor & Francis
Endometrial cancer (EC) is now one of the most common malignant tumors in young
women. In all, 90% of young patients with EC have a high expression of progesterone recep …