Alzheimer's disease (AD) is a heterogeneous neurodegenerative disease with multifaceted
neuropathological disorders. AD is characterized by intracellular accumulation of …

Agmatine, a naturally occurring polyamine derived from arginine via arginine
decarboxylase, has been shown to play multifaceted roles in the mammalian body …

Background Sacubitril acts to inhibit neprilysin and as neprilysin is involved in amyloid-beta
degradation in the central nervous system, and there is concern that sacubitril/valsartan may …

Background Spermidine is a natural biologically active substance that has widespread
influences on the body. Objective This study aims to enhance our understanding of the …

In this work, a simple, fast, and sensitive voltammetric method for the trace determination of
the alkaloid drug colchicine (Colc) using a 3D-printed device is described. The …

Hyperuricemia, the metabolic alteration that leads to gout or gouty arthritis, is increasing
worldwide. Glycoconjugated triazole-phthalimides show potent anti-inflammatory activity …

Comorbidities are a major issue in heart failure (HF), leading to frequent hospitalization and
high mortality. Comorbidities may be cardiovascular and non-cardiovascular. 1 Cognitive …

The most prevalent form of dementia, Alzheimer's disease (AD), is a neurological disorder
that causes gradual memory loss. AD is characterized by amyloid-beta plaques …

In the last few years, there has been a lot of interest in the effect of nutrition on cognitive
function, as it affects insulin signals inside the body, whose role is not limited to controlling …