RNA molecules can fold into intricate shapes that can provide an additional layer of control
of gene expression beyond that of their sequence. In this Review, we discuss the current …

This review is focused on the structural and physicochemical aspects of metal cation
coordination to G-Quadruplexes (GQ) and their effects on GQ stability and conformation. G …

Quadruplex-forming sequences are widely prevalent in human and other genomes,
including bacterial ones. These sequences are over-represented in eukaryotic telomeres …

Abstract G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that
have been first observed decades ago. Over the years, these four-stranded structural motifs …

Abstract G-quadruplexes (G4s), higher-order DNA and RNA secondary structures featuring
guanine-rich nucleic acid sequences with various conformations, are widely distributed in …

RNA structures in the untranslated regions (UTRs) of mRNAs influence post-transcriptional
regulation of gene expression. Much of the knowledge in this area depends on canonical …

The intriguing structural diversity in folded topologies available to guanine-rich nucleic acid
repeat sequences have made four-stranded G-quadruplex structures the focus of both basic …

Abstract RNA G-quadruplexes (G4s) are formed by G-rich RNA sequences in protein-coding
(mRNA) and non-coding (ncRNA) transcripts that fold into a four-stranded conformation …

G-quadruplex is a non-canonical nucleic acid structure formed by the folding of guanine rich
DNA or RNA. The conformation and function of G-quadruplex are determined by a number …

Although many biochemical and structural studies have demonstrated that DNA sequences
containing runs of adjacent guanines spontaneously fold into G-quadruplex DNA structures …