Chemotherapy is one of the prevailing methods used to treat malignant tumours, but the
outcome and prognosis of tumour patients are not optimistic. Cancer cells gradually …

Sarcomas are rare and complex malignancies that have been associated with a poor
prognostic outcome. Over the last few decades, traditional treatment with surgery and/or …

Primary cardiac angiosarcoma is relatively rare, and most cases involve metastasis at the
time of diagnosis. The median survival time is 14 months for patients who can be treated …

Zn0. 5Fe2. 5O4 nanoparticles (NPs) of 22 nm are synthesized by a one-pot approach and
coated with silica for magnetic hyperthermia agents. The NPs exhibit superparamagnetic …

Background The survival rate of osteosarcoma therapy still lags behind overall cancer
therapies due to the intrinsic or acquired drug resistance. Developing novel drug delivery …

Receptor tyrosine kinases (RTKs) inhibitors' activity in advanced osteosarcoma is significant
but short-lived. To prevent or at least delay drug resistance, we explored a vertical inhibition …

Ethnopharmacological relevance The milky sap or the aboveground part of the plant
Euphorbia lunulata has long been used by Chinese people to treat noncancerous growths …

A subset of soft tissue sarcomas often harbors recurrent fusions involving protein kinases.
While some of these fusion events have shown utility in arriving at a precise diagnosis, novel …

Euphorbia lunulata Bunge (ELB) is a traditional Chinese medicine possessing the functions
of expectoration, cough relief, asthma relief, detoxification, and itching relief. Modern …

Currently, the only available treatments for Trypanosoma cruzi are benznidazole (Bz) and
nifurtimox (Nfx). The mechanisms of action and resistance to these drugs in this parasite are …