Ebola virus disease
ST Jacob, I Crozier, WA Fischer, A Hewlett… - Nature reviews Disease …, 2020 - nature.com
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …
Monocytes and macrophages in COVID-19: Friends and foes
S Meidaninikjeh, N Sabouni, HZ Marzouni, S Bengar… - Life sciences, 2021 - Elsevier
The COVID-19 is a novel infectious disease caused by SARS-CoV-2 and is known as a
pandemic emergency that has led to a high rate of mortality throughout the world. Evidence …
pandemic emergency that has led to a high rate of mortality throughout the world. Evidence …
Ebola haemorrhagic fever
H Feldmann, TW Geisbert - The Lancet, 2011 - thelancet.com
Ebola viruses are the causative agents of a severe form of viral haemorrhagic fever in man,
designated Ebola haemorrhagic fever, and are endemic in regions of central Africa. The …
designated Ebola haemorrhagic fever, and are endemic in regions of central Africa. The …
Pathogenicity and virulence of Marburg virus
Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks
occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever …
occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever …
Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors
Monocytes are effectors of the inflammatory response to microbes. Human CD14+
monocytes specialize in phagocytosis and production of reactive oxygen species and …
monocytes specialize in phagocytosis and production of reactive oxygen species and …
Filovirus pathogenesis and immune evasion: insights from Ebola virus and Marburg virus
I Messaoudi, GK Amarasinghe, CF Basler - Nature Reviews …, 2015 - nature.com
Ebola viruses and Marburg viruses, members of the filovirus family, are zoonotic pathogens
that cause severe disease in people, as highlighted by the latest Ebola virus epidemic in …
that cause severe disease in people, as highlighted by the latest Ebola virus epidemic in …
Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection
TW Geisbert, LE Hensley, T Larsen, HA Young… - The American journal of …, 2003 - Elsevier
Ebola virus (EBOV) infection causes a severe and fatal hemorrhagic disease that in many
ways appears to be similar in humans and nonhuman primates; however, little is known …
ways appears to be similar in humans and nonhuman primates; however, little is known …
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus
AS Kondratowicz, NJ Lennemann… - Proceedings of the …, 2011 - National Acad Sciences
The glycoproteins (GP) of enveloped viruses facilitate entry into the host cell by interacting
with specific cellular receptors. Despite extensive study, a cellular receptor for the deadly …
with specific cellular receptors. Despite extensive study, a cellular receptor for the deadly …
Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis
N Wauquier, P Becquart, C Padilla… - PLoS neglected …, 2010 - journals.plos.org
Background Ebolavirus species Zaire (ZEBOV) causes highly lethal hemorrhagic fever,
resulting in the death of 90% of patients within days. Most information on immune responses …
resulting in the death of 90% of patients within days. Most information on immune responses …
Pathogenesis of the viral hemorrhagic fevers
S Paessler, DH Walker - Annual Review of Pathology …, 2013 - annualreviews.org
Four families of enveloped RNA viruses, filoviruses, flaviviruses, arenaviruses, and
bunyaviruses, cause hemorrhagic fevers. These viruses are maintained in specific natural …
bunyaviruses, cause hemorrhagic fevers. These viruses are maintained in specific natural …