Acute inflammatory diseases such as acute colitis, kidney injury, liver failure, lung injury,
myocardial infarction, pancreatitis, septic shock, and spinal cord injury are significant causes …

Radiation-induced pulmonary fibrosis (RIPF) is a general and fatal side effect of
radiotherapy, while the pathogenesis has not been entirely understood yet. By now, there is …

Research has advanced considerably since the first clinical trial of human mesenchymal
stem cells (MSCs) in the early 1990s. During this period, our understanding of MSC biology …

Pulmonary fibrosis (PF) is the end stage of severe lung diseases, in which the lung
parenchyma is replaced by fibrous scar tissue. The result is a remarkable reduction in …

Early cell biology reports demonstrated the presence of cells with stem-like properties in
bone marrow, with both hematopoietic and mesenchymal lineages. Over the years, various …

Multiple efforts are currently underway to control and treat severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), causing coronavirus disease 2019 (COVID-19) …

Interstitial lung disease (ILD) involves persistent inflammation and fibrosis, leading to
respiratory failure and even death. Adult tissue-derived mesenchymal stem cells (MSCs) …

Purpose: Acute pancreatitis (AP) is an inflammatory disorder distinguished by tissue injury
and inflammation of the pancreas. Using paracrine potential of mesenchymal stem cells …

Acute respiratory distress syndrome (ARDS)/acute lung injury (ALI) is a severe clinical
respiratory failure disorder associated with chronic pathology and disability and has a …

Mesenchymal stromal cells (MSCs) have been found to be safe and effective in a wide
range of animal models of human disease. MSCs have been tested in thousands of clinical …