CK2 genes are overexpressed in many human cancers, and most often overexpression is
associated with worse prognosis. Site-specific expression in mice leads to cancer …

CK2 is a protein kinase involved in several human diseases (ranging from neurological and
cardiovascular diseases to autoimmune disorders, diabetes, and infections, including …

The association of protein kinase CK2 (formerly casein kinase II or 2) with cell growth and
proliferation in cells was apparent at early stages of its investigation. A cancer-specific role …

Naturally occurring tumors in dogs are well-established models for several human cancers.
Domestic cats share many of the benefits of dogs as a model (spontaneous cancers …

Abstract Protein kinase CSNK2 (CK2) is a pleiotropic serine/threonine kinase frequently
dysregulated in solid and hematologic malignancies. To consolidate a wide range of …

Introduction: The conventional term 'casein kinase'(CK) denotes three classes of kinases–
CK1, CK2 and Golgi-CK (G-CK)/Fam20C (family with sequence similarity 20, member C) …

The Protein kinase CK2 (formerly known as casein kinase 2) is a highly conserved
serine/threonine kinase overexpressed in various human carcinomas and its high …

Introduction Targeted therapies for aggressive breast cancers like triple negative breast
cancer (TNBC) are needed. The use of small interfering RNAs (siRNAs) to disable …

Background: More than a century ago, Paul Ehrlich proposed the idea of a drug working as
a “magic bullet” that selectively eliminates diseased cells without harming the surrounding …

Glioblastoma multiforme (GBM) remains the deadliest brain tumor in adults. GBM tumors are
also notorious for drug and radiation resistance. To inhibit GBMs more effectively, polymalic …