Role of reactive oxygen species in myelodysplastic syndromes

Q Jing, C Zhou, J Zhang, P Zhang, Y Wu, J Zhou… - Cellular & Molecular …, 2024 - Springer
Reactive oxygen species (ROS) serve as typical metabolic byproducts of aerobic life and
play a pivotal role in redox reactions and signal transduction pathways. Contingent upon …

Targeting the tumor microenvironment in acute myeloid leukemia: The future of immunotherapy and natural products

C Hino, B Pham, D Park, C Yang, MHK Nguyen, S Kaur… - Biomedicines, 2022 - mdpi.com
The tumor microenvironment (TME) plays an essential role in the development, proliferation,
and survival of leukemic blasts in acute myeloid leukemia (AML). Within the bone marrow …

An efficient computer vision-based approach for acute lymphoblastic leukemia prediction

A Almadhor, U Sattar, A Al Hejaili… - Frontiers in …, 2022 - frontiersin.org
Leukemia (blood cancer) diseases arise when the number of White blood cells (WBCs) is
imbalanced in the human body. When the bone marrow produces many immature WBCs …

Beta-tocotrienol exhibits more cytotoxic effects than gamma-tocotrienol on breast cancer cells by promoting apoptosis via a P53-independent PI3-kinase dependent …

M Idriss, MH Hodroj, R Fakhoury, S Rizk - Biomolecules, 2020 - mdpi.com
Studies on tocotrienols have progressively revealed the benefits of these vitamin E isoforms
on human health. Beta-tocotrienol (beta-T3) is known to be less available in nature …

The pro-apoptotic effect of a Terpene-rich Annona cherimola leaf extract on leukemic cell lines

C Ammoury, M Younes, M El Khoury… - … and alternative medicine, 2019 - Springer
Abstract Background The edible fruit Annona cherimola has previously shown many
nutritional and medicinal properties. The current study evaluates the anti-cancer and anti …

Nettle tea inhibits growth of acute myeloid leukemia cells in vitro by promoting apoptosis

MH Hodroj, NH Al Bast, RI Taleb, J Borjac, S Rizk - Nutrients, 2020 - mdpi.com
Urtica dioica (UD), commonly known as “stinging nettle”, is a herbaceous flowering plant that
is a widely used agent in traditional medicine worldwide. Several formulations of UD leaf …

The selective anti-proliferative and pro-apoptotic effect of A. cherimola on MDA-MB-231 breast cancer cell line

M Younes, C Ammoury, T Haykal, L Nasr… - … medicine and therapies, 2020 - Springer
Background Herbal medicines have been a major target for numerous studies through the
past years as an alternative treatment for cancer, mainly due to their minimal effects on …

Transcriptomic analysis of the anticancer effects of annatto tocotrienol, delta-tocotrienol and gamma-tocotrienol on chondrosarcoma cells

KL Pang, LC Foong, N Abd Ghafar, IN Soelaiman… - Nutrients, 2022 - mdpi.com
Previous studies have demonstrated the anticancer activities of tocotrienol on several types
of cancer, but its effects on chondrosarcoma have never been investigated. Therefore, this …

Telomerase Inhibition in the Treatment of Leukemia: A Comprehensive Review

E Bartoszewska, K Molik, M Woźniak, A Choromańska - Antioxidants, 2024 - mdpi.com
Leukemia, characterized by the uncontrolled proliferation and differentiation blockage of
myeloid or lymphoid precursor cells, presents significant therapeutic challenges despite …

The impact of collaborative research: A case study in a developing country

M Al-Abbas, SS Saab - 2020 4th International Symposium on …, 2020 - ieeexplore.ieee.org
Collaborative research has become a viable and strategic engagement for universities and
scholars. Researchers often take part in grants and share scarce resources while gaining …